Evidence map›Paper›PMID 31045790›Full record

ArticleMedicine2019

The effect of anti-gravity treadmill training for knee osteoarthritis rehabilitation on joint pain, gait, and EMG: Case report.

Junjie Liang, Shijuan Lang, Yuxin Zheng, Yujue Wang, Hongxin Chen, Jinyu Yang, Zhiwei Luo, Qiang Lin, Haining Ou

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04299568 (Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population.), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04299568 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population.

TypeinterventionalSponsorFoundation University IslamabadRan2020 to 2020Enrolled50ConditionsOsteo Arthritis KneeArmsAnti gravity treadmill training, Physical Therapy
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. MicroRNA-199-3p up-regulation enhances chondrocyte proliferation and inhibits apoptosis in knee osteoarthritis via DNMT3A repression.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junjie LiangDepartment of Rehabilitation, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Shijuan Lang
Yuxin Zheng
Yujue Wang
Hongxin Chen
Jinyu Yang
Zhiwei Luo
Qiang Lin
Haining Ou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo date, the anti-gravity treadmill (AlterG), as a representative method of Lower body positive pressure (LBPP) treadmills, has been rarely reported for knee osteoarthritis (KOA) rehabilitation. The purpose of this case study was to setup the clinical protocol example for AlterG intervention on KOA and evaluate treatment effectiveness by 3D gait analysis combined with free EMG to explore the kinematic gait parameter changes. PATIENT CONCERNS: A 65-year-old female patient (BMI = 26, mild obesity) undergoing "more than 7 years of KOA." The activity of the right knee joint was obviously limited and she suffered from severe pain over the past month. DIAGNOSIS: Due to the patient's symptoms and radiographic findings, she was diagnosed with acute attack of KOA.

interventionsThe patient has performed clinical function evaluation and gait analysis combined at pretreatment, post-treatment, and 4 months follow-up assessment. AlterG training was performed 6 days/week for 2 weeks, with up to 30 min of training per session. The training protocol included two major parts, walking and squatting in AlterG. OUTCOMES: After 2 weeks of AlterG intervention, the 10-m walking test (10 MWT) and Timed-up-and-go (TUG) test improved significantly post-treatment, whereas the Visual Analog Scale (VAS) score decreased post-treatment. The Modified Barthel Index improved post-treatment and the patient restored basic community walk after treatment. The temporal parameter results showed that stride length (%height), mean velocity (%height), and cadence gradually increased before treatment, after treatment, and at 4-month follow-up. The right range of motion (ROM) of knee flexion-extension were gradually increased. Meanwhile, the synchronized EMG data showed that the RMS (root means square) values of the rectus femoris, semitendinosus, and biceps femoris at post-treatment were improved to different degrees than at pretreatment.

conclusionWe found that for this patient with KOA, AlterG relieved pain, and was also effective at improving spatio-temporal parameters, knee flexion/extension gait pattern, and corresponding muscle strength, thereby restoring certain community activities.

Indexed as

GaitAgedArthralgiaBiomechanical PhenomenaElectromyographyExercise TherapyFemaleHumansMuscle, SkeletalOsteoarthritis, KneeRange of Motion, ArticularWalking Speed

Identifiers

PMID31045790
PMCPMC6504276

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.