ArticleMedicine2019
The effect of anti-gravity treadmill training for knee osteoarthritis rehabilitation on joint pain, gait, and EMG: Case report.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04299568 (Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population.), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of aerobic exercises for knee osteoarthritis: a network meta analysis of randomized clinical trials.Journal of orthopaedic surgery and research · 2025Pooled it
- The Effectiveness of closed kinetic chain exercises in individuals with knee osteoarthritis: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Effects of Anti-Gravity Treadmill Training on Functional Outcomes After Total Hip Arthroplasty: A Randomized Controlled Trial.Acta medica academica · 2026Trial
- Effect of lower body positive pressure aerobic training on fall risk in patients with diabetic polyneuropathy: randomized controlled trial.European journal of physical and rehabilitation medicine · 2022Trial
- Effects of lower body positive pressure treadmill on functional improvement in knee osteoarthritis: A randomized clinical trial study.World journal of clinical cases · 2021Trial
- Effectiveness of Graded Weight-Bearing Exercises on Pain, Function, Proprioception, and Muscle Strength in Individuals with Knee Osteoarthritis: A Randomized Controlled Trial.Journal of clinical medicine · 2025Article
- Gait Analysis with an Upper Limb Prosthesis in a Child with Thrombocytopenia-Absent Radius Syndrome.Journal of clinical medicine · 2025Article
- Anti-gravity treadmill training benefits the post-operative rehabilitation of ACL reconstruction and the effects on the muscular atrophy and balance ability: a cohort study and 1y follow-up.Frontiers in sports and active living · 2025Article
- Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights.Frontiers in pharmacology · 2025Article
- General Treatments Promoting Independent Living in Parkinson's Patients and Physical Therapy Approaches for Improving Gait-A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2024Review
- Does Walking Have an Association with Osteoarthritis? A Two-Sample Mendelian Randomization Analysis.Clinical interventions in aging · 2024Review
- Integrative approach to pedobarography and pelvis-trunk motion for knee osteoarthritis detection and exploration of non-radiographic rehabilitation monitoring.Frontiers in bioengineering and biotechnology · 2024Article
- High intensity interval training attenuates osteoarthritis-associated hyperalgesia in rats.The journal of physiological sciences : JPS · 2023Article
- Article
- Review
- MicroRNA-199-3p up-regulation enhances chondrocyte proliferation and inhibits apoptosis in knee osteoarthritis via DNMT3A repression.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021Article
- Effect of acupuncture combined with early rehabilitation training on postoperative dysfunction and quality of life of patients undergoing total knee arthroplasty.American journal of translational research · 2021Article
- Walking on the Moon: A randomized clinical trial on the role of lower body positive pressure treadmill training in post-stroke gait impairment.Journal of advanced research · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo date, the anti-gravity treadmill (AlterG), as a representative method of Lower body positive pressure (LBPP) treadmills, has been rarely reported for knee osteoarthritis (KOA) rehabilitation. The purpose of this case study was to setup the clinical protocol example for AlterG intervention on KOA and evaluate treatment effectiveness by 3D gait analysis combined with free EMG to explore the kinematic gait parameter changes. PATIENT CONCERNS: A 65-year-old female patient (BMI = 26, mild obesity) undergoing "more than 7 years of KOA." The activity of the right knee joint was obviously limited and she suffered from severe pain over the past month. DIAGNOSIS: Due to the patient's symptoms and radiographic findings, she was diagnosed with acute attack of KOA.
interventionsThe patient has performed clinical function evaluation and gait analysis combined at pretreatment, post-treatment, and 4 months follow-up assessment. AlterG training was performed 6 days/week for 2 weeks, with up to 30 min of training per session. The training protocol included two major parts, walking and squatting in AlterG. OUTCOMES: After 2 weeks of AlterG intervention, the 10-m walking test (10 MWT) and Timed-up-and-go (TUG) test improved significantly post-treatment, whereas the Visual Analog Scale (VAS) score decreased post-treatment. The Modified Barthel Index improved post-treatment and the patient restored basic community walk after treatment. The temporal parameter results showed that stride length (%height), mean velocity (%height), and cadence gradually increased before treatment, after treatment, and at 4-month follow-up. The right range of motion (ROM) of knee flexion-extension were gradually increased. Meanwhile, the synchronized EMG data showed that the RMS (root means square) values of the rectus femoris, semitendinosus, and biceps femoris at post-treatment were improved to different degrees than at pretreatment.
conclusionWe found that for this patient with KOA, AlterG relieved pain, and was also effective at improving spatio-temporal parameters, knee flexion/extension gait pattern, and corresponding muscle strength, thereby restoring certain community activities.
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