Evidence map›Paper›PMID 31045569›Full record

ArticleActa crystallographica. Section F, Structural biology communications2019

High-resolution crystal structure of the reduced Grx1 from Saccharomyces cerevisiae.

Shadi Maghool, Sharon La Fontaine, Megan J Maher

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shadi MaghoolDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.
Sharon La FontaineSchool of Life and Environmental Sciences, Deakin University, Melbourne, Victoria, Australia.
Megan J MaherDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.
La Trobe University · AUDeakin University · AU

Funding

Australian Research Council DP140102746
6 · The paper itself

Abstract

Grx1, a cytosolic thiol-disulfide oxidoreductase, actively maintains cellular redox homeostasis using glutathione substrates (reduced, GSH, and oxidized, GSSG). Here, the crystallization of reduced Grx1 from the yeast Saccharomyces cerevisiae (yGrx1) in space group P2

Indexed as

Amino Acid SequenceCatalytic DomainCloning, MolecularCrystallography, X-RayCysteineEscherichia coliGene ExpressionGenetic VectorsGlutaredoxinsGlutathioneModels, MolecularOxidation-ReductionProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Interaction Domains and MotifsCysteineGlutaredoxinsGlutathioneGrx1 protein, S cerevisiaeRecombinant ProteinsSaccharomyces cerevisiae ProteinsglutaredoxinGrx1reduced formSaccharomyces cerevisiae

Identifiers

PMID31045569
PMCPMC6497100
OpenAlexW2940663674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.