Evidence map›Paper›PMID 31045494›Full record

ArticleeLife2019

The long non-coding RNA

Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper and 5 more

Erratum issuedAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Guidelines for mitochondrial RNA analysis.Molecular therapy. Nucleic acids · 2024
    Review
  13. Non-coding RNA research · 2024
    Review
  14. Review
  15. Unveiling the Hidden Regulators: The Impact of lncRNAs on Zoonoses.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Review
  18. Breast Cancer Chemoresistance: Insights into the Regulatory Role of lncRNA.International journal of molecular sciences · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Tamara M SireyMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0001-5606-2858
Kenny RobertsMRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.ORCID http://orcid.org/0000-0001-6155-0821
Wilfried HaertyMRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.ORCID https://orcid.org/0000-0003-0111-191X
Oscar Bedoya-ReinaMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.
Sebastian Rogatti-GranadosMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0002-8438-7999
Jennifer Y TanMRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.
Nick LiMRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.
Lisa C HeatherDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID https://orcid.org/0000-0002-7246-1338
Roderick N CarterUniversity/British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Sarah CooperDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Andrew J FinchMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0002-8065-4623
Jimi WillsMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0003-1669-007X
Nicholas M MortonUniversity/British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0001-8218-8462
Ana Claudia MarquesMRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.ORCID http://orcid.org/0000-0001-5174-8092
Chris P PontingMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0003-0202-7816

Funding

British Heart Foundation FS/17/58/33072Diabetes UK 11/0004175European Research Council 249869Medical Research Council MC_UU_00007/15
6 · The paper itself

Abstract

To generate energy efficiently, the cell is uniquely challenged to co-ordinate the abundance of electron transport chain protein subunits expressed from both nuclear and mitochondrial genomes. How an effective stoichiometry of this many constituent subunits is co-ordinated post-transcriptionally remains poorly understood. Here we show that

Indexed as

Gene Expression RegulationAnimalsCell LineElectron Transport Complex IGene Expression ProfilingHumansMiceMicroRNAsMitochondriaRNA, Long NoncodingElectron Transport Complex IMicroRNAsMIRN488 microRNA, humanRNA, Long Noncodingbiochemistrychemical biologyenergy metabolismgeneticsgenomicshumanlong noncoding RNAmiRNAmitochondriamousepost-transcriptional regulation

Identifiers

PMID31045494
PMCPMC6542586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.