Evidence map›Paper›PMID 31045413›Full record

ArticleJournal of abnormal psychology2019

Reward processing and future life stress: Stress generation pathway to depression.

Daniel M Mackin, Roman Kotov, Greg Perlman, Brady D Nelson, Brandon L Goldstein, Greg Hajcak, Daniel N Klein

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. A Bio-Psycho-Social Approach to Understanding Optimism and Pessimism in Response to Stress.European journal of investigation in health, psychology and education · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Longitudinal Associations Between Reward Responsiveness and Depression Across Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Environmental Contributions to Anhedonia.Current topics in behavioral neurosciences · 2022
    Review
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Daniel M MackinDepartment of Psychology.ORCID 0000-0002-2188-2968
Roman KotovDepartments of Psychiatry and Psychology.
Greg PerlmanDepartment of Psychiatry.
Brady D NelsonDepartment of Psychology.
Brandon L GoldsteinDepartment of Psychology.
Greg HajcakDepartment of Psychology, Florida State University.
Daniel N KleinDepartment of Psychology.ORCID 0000-0003-4582-6669
Florida State University · US

Funding

Personality Development and Vulnerability to First-Episode DepressionR01MH093479 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KOTOV, ROMAN I · 2012 to 2016
$3.3M
Gene Expression and Vulnerability to DepressionR56MH117116 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KLEIN, DANIEL N, KOTOV, ROMAN I · 2018 to 2019
$1.5M
National Institute of Mental HealthNIMH NIH HHS R01 MH093479NIMH NIH HHS R56 MH117116
6 · The paper itself

Abstract

Blunted reward sensitivity and life stress are each depressogenic. Additionally, individuals with clinical and psychosocial vulnerabilities are prone to experience or evoke dependent life stressors (e.g., interpersonal conflict) that, in turn, increase depression risk. However, no previous study has investigated the role of neural vulnerability factors in generating life stress. Therefore, the current study investigated whether a neural measure of reward sensitivity prospectively predicts the generation of life stress, which in turn mediates effects of these neural processes on subsequent depression. Participants were 467 never-depressed adolescent girls. Using event-related potentials, neural sensitivity to the difference between monetary reward and loss (the Reward Positivity [RewP]) was assessed at baseline. Negative life events were assessed twice via interview over the ensuing 18 months, yielding an index of total life stress over the follow-up period. A self-report dimensional measure of depression symptoms was administered at baseline and follow-up. After accounting for baseline age, depression, and race, a blunted RewP predicted greater dependent, but not independent, life stress over the follow-up. Mediation analyses revealed a significant indirect effect of the RewP on follow-up depression through dependent, but not independent, life stress. Our results suggest that neural processing reward and loss plays a crucial role in depressogenic stress generation. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

RewardAdolescentConflict, PsychologicalDepressive DisorderEvoked PotentialsFemaleHumansInterpersonal RelationsProspective StudiesRisk FactorsStress, Psychological

Identifiers

PMID31045413
PMCPMC6586409
OpenAlexW2943737389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.