ArticleJournal of the American Geriatrics Society2019
Moving Frailty Toward Clinical Practice: NIA Intramural Frailty Science Symposium Summary.
Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 8 syntheses or guidelines pooled it, 178 citations in OpenAlex.
- Reporting race and ethnicity in aging in place research: A systematic review.The Gerontologist · 2026Pooled it
- Frailty Screening Using the Risk Analysis Index: A User Guide.Joint Commission journal on quality and patient safety · 2025Pooled it
- Prevalence of Frailty Among Chinese Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.International journal of public health · 2023Pooled it
- The Association of Frailty with Outcomes after Cancer Surgery: A Systematic Review and Metaanalysis.Annals of surgical oncology · 2022Pooled it
- Efficacy of power training to improve physical function in individuals diagnosed with frailty and chronic disease: A meta-analysis.Physiological reports · 2022Pooled it
- Associations between self-reported masticatory dysfunction and frailty: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Frailty and risk of complications in head and neck oncologic surgery. Systematic review and dose-response meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2021Pooled it
- Medico-legal assessment of personal damage in older people: report from a multidisciplinary consensus conference.International journal of legal medicine · 2020Pooled it
- Randomized phase 2b dose-escalation trial of stem cell therapy with laromestrocel for aging frailty.Cell stem cell · 2026Trial
- Lack of Immune Resilience Negatively Affects Physical Resilience: Results From the InCHIANTI Follow-Up Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- Association Between Long-Term Aspirin Use and Frailty in Men: The Physicians' Health Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Trial
- Impact of Multidomain Lifestyle Intervention on Frailty Through the Lens of Deficit Accumulation in Adults with Type 2 Diabetes Mellitus.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Identification of Frailty Subtypes in African American Adults With and Without Type 2 Diabetes: A Latent Class Analysis From the Jackson Heart Study.Diabetes, obesity & metabolism · 2026Article
- Predictive value of the risk analysis index for 30-day mortality following surgical management of thoracolumbar vertebral body fractures.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Leveraging mitochondrial stress to improve healthy aging.Sports medicine and health science · 2026Review
- Baseline and long-term frailty transitions and rapid estimated glomerular filtration rate decline: evidence from two large population-based studies.Renal failure · 2025Article
- Addressing Frailty in Cardiology: Identifying Barriers Faced by Cardiologists and Health Care Professionals in Asia.JACC. Asia · 2025Article
- A survey on the trajectory of frailty in the middle-aged and elderly population in the Chengdu community: a retrospective observational study.BMC public health · 2025Observational
- Prevalence, impact on quality of life, and predictive factors of coexistence of overactive bladder and underactive bladder in men.Scientific reports · 2025Article
- Risk Analysis Index for Estimation of 30-Day Postoperative Mortality in Hip Fractures.JAMA network open · 2025Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 10 institutions in 3 countries.
Funding
Abstract
Frailty has long been an important concept in the practice of geriatric medicine and in gerontological research, but integration and implementation of frailty concepts into clinical practice in the United States has been slow. The National Institute on Aging (NIA) Intramural Research Program and the Johns Hopkins Older Americans Independence Center sponsored a symposium to identify potential barriers that impede the movement of frailty into clinical practice and to highlight opportunities to facilitate the further integration of frailty into clinical practice. Primary and subspecialty care providers, and investigators working to integrate and translate new biological aging knowledge into more specific preventive and treatment strategies for frailty provided the meeting content. Recommendations included a call for more specific language that clarifies conceptual differences between frailty definitions and measurement tools; the development of randomized controlled trials to test whether specific intervention strategies for a variety of conditions differently affect frail and non-frail individuals; development of implementation studies and therapeutic trials aimed at tailoring care as a function of pragmatic frailty markers; the use of deep learning and dynamic systems approaches to improve the translatability of findings from epidemiological studies; and the incorporation of advances in aging biology, especially focused on mitochondria, stem cells, and senescent cells, toward the further development of biologically targeted intervention and prevention strategies that can be used to treat or prevent frailty. J Am Geriatr Soc 67:1559-1564, 2019.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.