Evidence map›Paper›PMID 31045243›Full record

ArticleThe Journal of physiology2019

Potentiating α

Toshihiro Nomura, Nicole A Hawkins, Jennifer A Kearney, Alfred L George, Anis Contractor

Abstract read
In one paragraph

Article in The Journal of physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. ENX-101, a GABAEpilepsia · 2025
    Article
  3. Article
  4. Fine mapping and candidate gene analysis of Dravet syndrome modifier loci on mouse chromosomes 7 and 8.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Gabra2 is a genetic modifier of Dravet syndrome in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2021
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Toshihiro NomuraDepartment of Physiology, Northwestern University, Chicago, IL, 60611, USA.ORCID 0000-0001-8786-831X
Nicole A HawkinsDepartment of Pharmacology Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Jennifer A KearneyDepartment of Pharmacology Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Alfred L GeorgeDepartment of Pharmacology Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Anis ContractorDepartment of Physiology, Northwestern University, Chicago, IL, 60611, USA.ORCID 0000-0002-5131-2536

Funding

The role of glutamate receptors in compulsive and perseverative behaviorR01MH099114 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CONTRACTOR, ANIS · 2012 to 2022
$4.5M
Genetic Modifiers of Childhood EpilepsyR01NS084959 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KEARNEY, JENNIFER A · 2014 to 2024
$4.2M
NIMH NIH HHS R01 MH099114NINDS NIH HHS R01 NS084959
6 · The paper itself

Abstract

key pointsDravet syndrome mice (Scn1a ABSTRACT: GABA

Indexed as

AnimalsElectrophysiological PhenomenaEpilepsies, MyoclonicFeverGABA ModulatorsGene Expression RegulationHeterocyclic Compounds, 2-RingMice, Inbred StrainsNAV1.1 Voltage-Gated Sodium ChannelProtein SubunitsReceptors, GABA-ASeizures4-amino-8-(2-fluoro-6-methoxy-phenyl)-N-propylcinnoline-3-carboxamideGABA ModulatorsHeterocyclic Compounds, 2-RingNAV1.1 Voltage-Gated Sodium ChannelProtein SubunitsReceptors, GABA-AScn1a protein, mouseDravet syndromeGABA receptorα2 subunit

Identifiers

PMID31045243
PMCPMC7087452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.