Evidence map›Paper›PMID 31044430›Full record

ArticleJournal of surgical oncology2019

Postbiliary drainage rates of cholangitis are impacted by procedural technique for patients with supra-ampullary cholangiocarcinoma: A SEER-Medicare analysis.

Christine M Kariya, Michael M Wach, Samantha M Ruff, Reed I Ayabe, Winifred M Lo, Madeline B Torres, Jessica L Petrick, Timothy S McNeel, Jeremy L Davis, Katherine A McGlynn and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Christine M KariyaSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
Michael M WachSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.ORCID http://orcid.org/0000-0002-7686-6076
Samantha M RuffSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
Reed I AyabeSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
Winifred M LoSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
Madeline B TorresSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
Jessica L PetrickMetabolic Epidemiology Branch, National Cancer Institute, Rockville, Maryland.
Timothy S McNeelInformation Management Services, Inc, Rockville, Maryland.
Jeremy L DavisSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
Katherine A McGlynnMetabolic Epidemiology Branch, National Cancer Institute, Rockville, Maryland.
Jonathan M HernandezSurgical Oncology Program, National Cancer Institute, Bethesda, Maryland.
National Cancer Institute · USInformation Management Services · US

Funding

Studies of Rare CancersZIACP010158 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MCGLYNN, KATHERINE · 2009 to 2025
$19.1M
Evaluating outcomes for patients with primary-metastatic gastrointestinal cancerZIABC011861 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HERNANDEZ, JONATHAN · 2019 to 2025
$166k
Intramural NIH HHS Z99 CA999999NIH Intramural Research Program
6 · The paper itself

Abstract

backgroundThe optimal approach to biliary drainage for patients with supra-ampullary cholangiocarcinoma remains undetermined. Violation of sphincter of Oddi results in bacterial colonization of bile ducts and may increase postdrainage infectious complications. We sought to determine if rates of cholangitis are affected by the type of drainage procedure.

methodsWe examined the Surveillance, Epidemiology, and End Results-Medicare linked database from 1991 to 2013 for cholangiocarcinoma. Biliary drainage procedures were categorized as sphincter of Oddi violating (SOV) or sphincter of Oddi preserving (SOP). Patients were stratified by resection.

resultsA total of 1914 patients were included in the final analysis. A total of 1264 patients did not undergo a postdrainage resection (SOP 83, SOV 1181) while 650 did undergo a postdrainage resection (SOP 26, SOV 624). For those patients not undergoing a postdrainage resection, the rate of cholangitis 90 days after an SOP procedure was 19% compared with 34% in the SOV cohort (P = 0.007). For those patients undergoing a postdrainage resection, the rate of cholangitis 90 days after an SOP procedure was less than 42.3% compared with 30% in the SOV cohort (P = 0.66).

conclusionFor patients with supra-ampullary cholangiocarcinoma that did not undergo resection, biliary drainage procedures that violated the sphincter of Oddi were associated with increased rates of cholangitis.

Indexed as

DrainageAgedAged, 80 and overBile Duct NeoplasmsCholangiocarcinomaCholangitisCohort StudiesFemaleHumansMaleMedicarePostoperative ComplicationsSEER ProgramUnited Statesbiliary drainagecholangiocarcinomacholangitisinfection

Identifiers

PMID31044430
PMCPMC6635029
OpenAlexW2943576648

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.