Evidence map›Paper›PMID 31044401›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Prognostic significance of post-stress reduction in left ventricular ejection fraction with adenosine stress in Jordanian patients with normal myocardial perfusion.

Omar S Obeidat, Abdullah Alhouri, Bayan Baniissa, Omar Alqaisi, Mohammad Akkawi, Heba Zyad, Omar Alrimawi, Mira Al Jabi, Saba Jaradat, Hamza Jawabreh and 3 more

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Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Omar S ObeidatDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Abdullah AlhouriDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Bayan BaniissaDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Omar AlqaisiDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Mohammad AkkawiDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Heba ZyadDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Omar AlrimawiDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Mira Al JabiDivision of Nuclear Medicine/Department of Radiology and Nuclear Medicine, University of Jordan, Queen Rania Street, Al Jubeiha, Amman, 11942, Jordan.
Saba JaradatDivision of Nuclear Medicine/Department of Radiology and Nuclear Medicine, University of Jordan, Queen Rania Street, Al Jubeiha, Amman, 11942, Jordan.
Hamza JawabrehDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Odai Al-BatshDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Othman AlarajDivision of Cardiology/Department of Medicine, University of Jordan, Amman, Jordan.
Malik E JuweidDivision of Nuclear Medicine/Department of Radiology and Nuclear Medicine, University of Jordan, Queen Rania Street, Al Jubeiha, Amman, 11942, Jordan. mjuweid@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe significance of post-stress reduction in left ventricular ejection fraction (LVEF) in patients with normal perfusion on adenosine stress/rest imaging remains controversial.

methodsConsecutive patients who underwent 2-day adenosine gated stress/rest

resultsOf 560 patients included in the study, 135 (24.1%) had a post-stress reduction in LVEF of ≥ 5%. Rest LVEF (P < 0.001), known history of CAD (P = 0.01) and transient ischemic dilatation ratio (P = 0.02) were independent predictors of LVEF reduction. Event-free survivals were similar in patients with and without ≥ 5% LVEF reduction (P = 0.8). The unadjusted hazard ratio (95% CI) for cardiac events for ≥ 5% LVEF reduction was 1.09 (0.55-2.15), P = 0.81, while the hazard ratio adjusted for known history of CAD, smoking, post-stress LVEF and peak heart rate was 0.87 (0.44-1.75), P = 0.71.

conclusionsSignificant post-adenosine reduction in LVEF occurs in about one-fourth of patients with normal perfusion but does not confer adverse prognosis compared with patients without such reduction.

Indexed as

Exercise TestAdenosineAgedCardiovascular DiseasesFemaleHumansJordanMaleMiddle AgedMyocardial Perfusion ImagingMyocardial RevascularizationPrognosisRadiopharmaceuticalsRestStroke VolumeSurvival RateAdenosineRadiopharmaceuticalsTechnetium Tc 99m Sestamibidiagnostic and prognostic applicationGated SPECTMPIvasodilators

Identifiers

PMID31044401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.