Evidence map›Paper›PMID 31044354›Full record

ReviewClinical reviews in allergy & immunology2019

Asthma and Allergies in the School Environment.

Brittany Esty, Perdita Permaul, Kristie DeLoreto, Sachin N Baxi, Wanda Phipatanakul

Open access · greenAbstract readReview
In one paragraph

Review in Clinical reviews in allergy & immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 51 citations in OpenAlex.

  1. Implementation of Coach McLungsBMC medical informatics and decision making · 2022
    Trial
  2. Breathing Easy: A Qualitative Analysis of School Nurse and Administrator Perspectives on Stock Inhalers and School-Based Asthma Management.The Journal of school nursing : the official publication of the National Association of School Nurses · 2026
    Article
  3. Dog exposure and subsequent asthma outcomes in children with asthma and allergy.The journal of allergy and clinical immunology. Global · 2026
    Article
  4. Article
  5. The effects of urban green space and road proximity to indoor traffic-related PMJournal of exposure science & environmental epidemiology · 2024
    Article
  6. Article
  7. Article
  8. Environmental radon and childhood asthma.Pediatric pulmonology · 2022
    Article
  9. Environmental Exposures Impact Pediatric Asthma Within the School Environment.Immunology and allergy clinics of North America · 2022
    Review
  10. Article
  11. Update on indoor allergens and their impact on pediatric asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brittany EstyDivision of Immunology, Boston Children's Hospital, 300 Longwood Avenue, Fegan Building, 6th Floor, Boston, MA, 02115, USA.
Perdita PermaulDivision of Pediatric Allergy and Immunology, Weil Cornell Medical College, New York, NY, USA.
Kristie DeLoretoAllergy and Asthma Awareness Initiative, Inc., Peabody, MA, USA.
Sachin N BaxiDivision of Immunology, Boston Children's Hospital, 300 Longwood Avenue, Fegan Building, 6th Floor, Boston, MA, 02115, USA.
Wanda PhipatanakulDivision of Immunology, Boston Children's Hospital, 300 Longwood Avenue, Fegan Building, 6th Floor, Boston, MA, 02115, USA. Wanda.Phipatanakul@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-8639-0473
Boston Children's Hospital · USCornell University · USHealth Awareness (United States) · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Controlling and preventing Asthma progression and Severity in Kids (CASK)U01AI126614 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2016 to 2023
$21.0M
Molecular Basis of Hyper lgE ImmunodeficiencyR01AI065617 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Talal Amine Chatila · 2006 to 2026
$10.9M
SICAS- Diversity SupplementU01AI110397 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2015 to 2020
$8.8M
Effect of IL-4RαR576 variant on response to Dupilumab in children with AsthmaU01AI143514 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHATILA, TALAL AMINE, PHIPATANAKUL, WANDA · 2019 to 2023
$8.4M
Environmental Risk Factors for Pediatric Sleep Disordered BreathingR01HL137192 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2017 to 2020
$3.5M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
Atopy, Leptin and Potential Biomarkers of Comorbid Obesity and Asthma in Inner-City SchoolchildrenK23AI123517 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PERMAUL, PERDITA · 2017 to 2021
$1.1M
NCATS NIH HHS UL1 TR001102NHLBI NIH HHS R01 HL137192NIAID NIH HHS K23 AI123517NIAID NIH HHS K24 AI106822NIAID NIH HHS L40 AI113791NIAID NIH HHS R01 AI065617NIAID NIH HHS U01 AI110397NIAID NIH HHS U01 AI126614NIAID NIH HHS U01 AI143514NIH HHS K23 AI 123517NIH HHS K24 AI 106822NIH HHS LRP #L40 AI113791NIH HHS R01 HL 137192NIH HHS U01 AI 110397
6 · The paper itself

Abstract

The school is a complex microenvironment of indoor allergens, pollutants, and other exposures. The school represents an occupational model for children and exposures in this environment have a significant health effect. Current research establishes an association between school exposure and asthma morbidity in children. This review will focus on common school environmental exposures (cockroach, rodents, cat, dog, classroom pets, dust mite, fungus, and pollution) and their impact on children with allergies and asthma. Understanding and evaluation of school-based environments is needed to help guide school-based interventions. School-based interventions have the potential for substantial benefit to the individual, school, community, and public health. However, there is a paucity data on school-based environmental interventions and health outcomes. The studies performed to date are small and cross-sectional with no control for home exposures. Randomized controlled school-based environmental intervention trials are needed to assess health outcomes and the cost-effectiveness of these interventions. The School Inner-City Asthma Intervention Study (SICAS 2), a NIH/NIAID randomized controlled clinical trial using environmental interventions modeled from successful home-based interventions, is currently underway with health outcome results pending. If efficacious, these interventions could potentially help further guide school-based interventions potentially with policy implications. In the meanwhile, the allergist/immunologist can continue to play a vital role in improving the quality of life in children with allergies and asthma at school through the use of the ADA policy and Section 504 of the Rehabilitation Act as well as encouraging adoption of toolkits to build successful school-based asthma programs and asthma-friendly schools.

Indexed as

Environmental ExposureSchoolsAir Pollution, IndoorAllergensAnimalsAsthmaCockroachesEarly Intervention, EducationalHumansHypersensitivityPetsRodentiaAllergensAllergenAsthmaEnvironmentPediatric asthmaPollutantSchoolSchool-based interventionSchool exposure

Identifiers

PMID31044354
PMCPMC6824974
OpenAlexW2943766978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.