Evidence map›Paper›PMID 31044344›Full record

ArticleFunctional & integrative genomics2019

Cryptochrome deletion in p53 mutant mice enhances apoptotic and anti-tumorigenic responses to UV damage at the transcriptome level.

Ayse Derya Cavga, Mehmet Tardu, Tuba Korkmaz, Ozlem Keskin, Nuri Ozturk, Attila Gursoy, Ibrahim Halil Kavakli

Abstract read
PubMed Publisher
In one paragraph

Article in Functional & integrative genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cancer, hear my battle CRY.Journal of pineal research · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ayse Derya CavgaChemical and Biological Engineering, Koc University, Istanbul, Turkey.
Mehmet TarduComputational Science Engineering, Koc University, Istanbul, Turkey.
Tuba KorkmazMolecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Ozlem KeskinChemical and Biological Engineering, Koc University, Istanbul, Turkey.
Nuri OzturkMolecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Attila GursoyComputer Engineering, Koc University, Istanbul, Turkey. agursoy@ku.edu.tr.
Ibrahim Halil KavakliChemical and Biological Engineering, Koc University, Istanbul, Turkey. hkavakli@ku.edu.tr.
Koç University · TRGebze Technical University · TR

Funding

Istanbul Kalkinma Ajansi ISTKA-TR/14/EVK/0039
6 · The paper itself

Abstract

Previous studies have demonstrated that deletion of cryptochrome (Cry) genes protects p53

Indexed as

ApoptosisDNA DamageTranscriptomeAnimalsCarcinogenesisCryptochromesFibroblastsMiceMice, KnockoutNeoplasms, ExperimentalSkinTumor Suppressor Protein p53Ultraviolet RaysCry1 protein, mouseCry2 protein, mouseCryptochromesTrp53 protein, mouseTumor Suppressor Protein p53CancerCircadian clockCryptochromep53RNA-seqTranscriptome

Identifiers

PMID31044344
OpenAlexW2943466159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.