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ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2019

Influence of chronotype on migraine characteristics.

Giovanna Viticchi, Lorenzo Falsetti, Matteo Paolucci, Claudia Altamura, Laura Buratti, Sergio Salvemini, Nicoletta Brunelli, Marco Bartolini, Fabrizio Vernieri, Mauro Silvestrini

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Relationship of sleep quality, chronotype, and obstructive sleep apnea with migraine in the elderly population.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2024
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Poor sleep quality in patients affected by migraine: a population study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  19. Genetics of the human circadian clock and sleep homeostat.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giovanna ViticchiNeurological Clinic, Marche Polytechnic University, Via Conca 1, 60100, Ancona, Italy. viticchi.g@gmail.com.ORCID http://orcid.org/0000-0002-1799-1563
Lorenzo FalsettiInternal and Subintensive Medicine, Ospedali Riuniti, Ancona, Italy.
Matteo PaolucciNeurology Unit, Campus Bio-Medico University, Rome, Italy.
Claudia AltamuraNeurology Unit, Campus Bio-Medico University, Rome, Italy.
Laura BurattiNeurological Clinic, Marche Polytechnic University, Via Conca 1, 60100, Ancona, Italy.
Sergio SalveminiNeurological Clinic, Marche Polytechnic University, Via Conca 1, 60100, Ancona, Italy.
Nicoletta BrunelliNeurology Unit, Campus Bio-Medico University, Rome, Italy.
Marco BartoliniNeurological Clinic, Marche Polytechnic University, Via Conca 1, 60100, Ancona, Italy.
Fabrizio VernieriNeurology Unit, Campus Bio-Medico University, Rome, Italy.
Mauro SilvestriniNeurological Clinic, Marche Polytechnic University, Via Conca 1, 60100, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate chronotype in migraine patients and possible influences on the clinical expression of the disease.

methodsDuring a one-year period, all consecutive patients admitted to two third-level headache centres with a new diagnosis of migraine were enrolled in a cross-sectional study. All subjects were submitted to the Morningness-Eveningness Questionnaire (MEQ-SA) and then classified in five different categories, from late to early-rising chronotype. Differences and trends among MEQ-SA categories and years from migraine onset, attacks' intensity and frequency were analysed first with analysis of variance, then with a multivariate/generalized linear model.

resultsOne hundred seventy one migraine patients were included. Early-rising patients showed a lower migraine attacks frequency and longer disease duration with respect to late-rising patients. The categorical variable containing the five circadian types was able to identify a significantly different trend both for the monthly attacks frequency and for the disease duration (p < 0.0001 and p < 0.0001, respectively, analysis of variance). The results were also confirmed after correction for main influencing variables (multivariate/generalized linear model). The intensity of migraine attacks was not influenced by chronotype.

conclusionsAccording to the results of the present study, chronotype seems to influence number and duration of migraine attacks. Although sleep-wake cycle is a well-recognized factor able to influence thalamic-cortical synchronization, it usually does not receive appropriate consideration during migraine patients' assessment.

Indexed as

AdultCircadian RhythmCross-Sectional StudiesFemaleHumansMaleMiddle AgedMigraine DisordersSleepTime FactorsWakefulnessCircadian rhythmHeadacheSleepSleep–wake cycle

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.