Evidence map›Paper›PMID 31044170›Full record

ArticleCommunications biology2019

The subthreshold-active K

Katiuscia Martinello, Elisabetta Giacalone, Michele Migliore, David A Brown, Mala M Shah

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. KThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. KCNQ Channels Enable Reliable Presynaptic Spiking and Synaptic Transmission at High Frequency.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  13. Poly-dipeptides produced fromProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
  15. The Role of KFrontiers in physiology · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Katiuscia Martinello1UCL School of Pharmacy University College London, London, WC1N 1AX UK.
Elisabetta Giacalone2Institute of Biophysics, National Research Council, 90146 Palermo, Italy.
Michele Migliore2Institute of Biophysics, National Research Council, 90146 Palermo, Italy.
David A Brown3Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT UK.
Mala M Shah1UCL School of Pharmacy University College London, London, WC1N 1AX UK.
University College London · GBNational Research Council · IT

Funding

Biotechnology and Biological Sciences Research Council BB/L000679/1Wellcome TrustWellcome Trust WT087363MA
6 · The paper itself

Abstract

Little is known about the properties and function of ion channels that affect synaptic terminal-resting properties. One particular subthreshold-active ion channel, the Kv7 potassium channel, is highly localized to axons, but its role in regulating synaptic terminal intrinsic excitability and release is largely unexplored. Using electrophysiological recordings together with computational modeling, we found that the K

Indexed as

Action PotentialsAnimalsCA3 Region, HippocampalCalciumComputational BiologyExcitatory Postsynaptic PotentialsKCNQ Potassium ChannelsMaleMossy Fibers, HippocampalNeuronal PlasticityPresynaptic TerminalsPyramidal CellsRatsRats, Sprague-DawleySynapsesSynaptic TransmissionCalciumKCNQ Potassium ChannelsCellular neuroscienceIon channels in the nervous system

Identifiers

PMID31044170
PMCPMC6486593
OpenAlexW2942460792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.