ArticleBiotechnology for biofuels2019
Combining directed evolution of pathway enzymes and dynamic pathway regulation using a quorum-sensing circuit to improve the production of 4-hydroxyphenylacetic acid in
Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 56 citations in OpenAlex.
- Quorum sensing-driven riboflavin-hyperproducing electroactive bacteria for enhanced bioelectricity generation from sludge: From modular optimization to process performance.Synthetic and systems biotechnology · 2027Article
- Ontogenetic shifts in the metabolomic profiles of Battus polydamas (Lepidoptera: Papilionidae: Troidini) Feeding on Aristolochia gigantea.Journal of chemical ecology · 2026Article
- Early prediction of bronchopulmonary dysplasia by urinary metabolomics: a case-control study.Thorax · 2026Observational
- Engineering non-P450 3-hydroxylase forSynthetic and systems biotechnology · 2025Article
- The metabolic engineering of Escherichia coli for the high-yield production of hypoxanthine.Microbial cell factories · 2024Article
- Identification of Urine Metabolic Markers of Stroke Risk Using Untargeted Nuclear Magnetic Resonance Analysis.International journal of molecular sciences · 2024Article
- Increasing the robustness of Escherichia coli for aromatic chemicals production through transcription factor engineering.Advanced biotechnology · 2024Article
- Advances in regulating vitamin KWorld journal of microbiology & biotechnology · 2023Review
- Construction of a plasmid-free L-leucine overproducing Escherichia coli strain through reprogramming of the metabolic flux.Biotechnology for biofuels and bioproducts · 2023Article
- Biosynthesis pathways of expanding carbon chains for producing advanced biofuels.Biotechnology for biofuels and bioproducts · 2023Review
- Engineering a Pseudomonas taiwanensis 4-coumarate platform for production of para-hydroxy aromatics with high yield and specificity.Metabolic engineering · 2023Article
- Multiple Metabolic Engineering Strategies to Improve Shikimate Titer inMetabolites · 2023Article
- Quorum Sensing as a Trigger That Improves Characteristics of Microbial Biocatalysts.Microorganisms · 2023Review
- Enhancing the Production of Pinene inBiology · 2022Article
- Application of quorum sensing system in microbial synthesis of valuable chemicals: a mini-review.World journal of microbiology & biotechnology · 2022Review
- Engineering for life in toxicity: Key to industrializing microbial synthesis of high energy density fuels.Engineering microbiology · 2022Review
- Biosensor-enabled pathway optimization in metabolic engineering.Current opinion in biotechnology · 2022Review
- Research progress of pathway and genome evolution in microbes.Synthetic and systems biotechnology · 2022Article
- Switching promotor recognition of phage RNA polymerase in silico along lab-directed evolution path.Biophysical journal · 2022Article
- Site-directed mutagenesis of the quorum-sensing transcriptional regulator SinR affects the biosynthesis of menaquinone in Bacillus subtilis.Microbial cell factories · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background4-Hydroxyphenylacetic acid (4HPAA) is an important building block for synthesizing drugs, agrochemicals, biochemicals, etc. 4HPAA is currently produced exclusively via petrochemical processes and the process is environmentally unfriendly and unsustainable. Microbial cell factory would be an attractive approach for 4HPAA production.
resultsIn the present study, we established a microbial biosynthetic system for the de novo production of 4HPAA from glucose in
conclusionWe have constructed an
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.