Evidence map›Paper›PMID 31043991›Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2019

Chemokine RANTES and IL-1β in mild therapeutic hypothermia-treated patients after out-of-hospital sudden cardiac arrest.

Jakub Podolec, Aleksander Trąbka-Zawicki, Rafał Badacz, Mateusz Siedliński, Marek Tomala, Krzysztof Bartuś, Jacek Legutko, Tadeusz Przewłocki, Krzysztof Żmudka, Anna Kabłak-Ziembicka

Open access · goldAbstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jakub PodolecDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Aleksander Trąbka-ZawickiDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Rafał BadaczDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Mateusz SiedlińskiDepartment of Internal and Agricultural Medicine, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Marek TomalaDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Krzysztof BartuśDepartment of Cardiovascular Surgery and Transplantology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Jacek LegutkoDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Tadeusz PrzewłockiDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Krzysztof ŻmudkaDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Anna Kabłak-ZiembickaDepartment of Interventional Cardiology, Jagiellonian University College of Medicine, John Paul II Hospital, Krakow, Poland.
Jagiellonian University · PLJohn Paul II Hospital · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCCL5/RANTES and IL-1β, which regulate the immune response, may have an impact on survival in patients with acute coronary syndrome (ACS) and sudden cardiac arrest (SCA).

aimTo evaluate levels of CCL5/RANTES and IL-1β in patients with ACS complicated by SCA, treated with coronary angioplasty (PCI) and mild therapeutic hypothermia (MTH), and these chemokines' impact on the 30- and 180-day survival. MATERIAL AND

methodsThirty-three unconscious patients admitted after SCA with ACS underwent PCI and MTH treatment. CCL5/RANTES and IL-1β were evaluated on admission (T0), at 12-24 h (T1) and at 48-72 h (T2). All-cause mortality was recorded at 30 and 180 days.

resultsWe observed a statistically significant decrease in median levels of CCL/RANTES at T0, T1 and T2 (24.69 ng/ml vs. 3.89 ng/ml vs. 2.71 ng/ml;

conclusionsAlthough CCL5/RANTES levels correlate with cardiac injury and heart failure markers and they decrease during MTH, they failed to predict early and late mortality. In contrast, IL-1β level was associated with 180-day survival.

Indexed as

chemokine RANTESIL-1βmild therapeutic hypothermiasudden cardiac arrest

Identifiers

PMID31043991
PMCPMC6488836
OpenAlexW2924116586

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.