Evidence map›Paper›PMID 31043911›Full record

ArticleIntegrative medicine (Encinitas, Calif.)2018

A Biomedical Approach Via Telemedicine in the Treatment of a Child With Sensory Processing Disorder Using Diet and High-dose Biotin Intervention: A Case Report.

Gail Clayton, Heather A Carrera, Edward R Martin, Demetrice Morrison, Abubakar A Bawazir

Abstract readCase Reports
In one paragraph

Article in Integrative medicine (Encinitas, Calif.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gail ClaytonAll authors are doctoral students in Clinical Nutrition at Maryland University of Integrative Health in Laurel, Maryland.
Heather A CarreraAll authors are doctoral students in Clinical Nutrition at Maryland University of Integrative Health in Laurel, Maryland.
Edward R MartinAll authors are doctoral students in Clinical Nutrition at Maryland University of Integrative Health in Laurel, Maryland.
Demetrice MorrisonAll authors are doctoral students in Clinical Nutrition at Maryland University of Integrative Health in Laurel, Maryland.
Abubakar A BawazirAll authors are doctoral students in Clinical Nutrition at Maryland University of Integrative Health in Laurel, Maryland.
Maryland University of Integrative Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe present the case of a 6-y-old boy who was diagnosed with sensory processing disorder with developmental language and learning delay. He was treated successfully with diet and high-dose biotin along with other nutrient support that resulted in resolution of abnormal sensory behaviors and improvement in language and learning. CASE/

interventionThe child was diagnosed with a presumed biotin deficiency from organic acids testing which revealed markers that reflected biotin deficiency despite supplementation with 300 mcg daily (AI = 12 mcg/d). Stool markers were also noted for low beneficial biotin producing microbiota. In the course of several months of high-dose biotin supplementation with herbal treatment for dysbiosis, he was able to subsequently transition from special needs classes requiring sensory support into mainstream classes as a neurotypical child with age appropriate language and learning skills and resolution of abnormal sensory behaviors.

conclusionThis case illustrates the importance of using functional nutrition labs to rule out nutrient imbalances that could be a cause of improper signaling in the brain, which can translate into delayed language, learning, and behavior disorders. Organic acids may reveal a much higher level of need of nutrients, especially when polymorphisms of enzymes are present that may be responsive, as this case demonstrates, to targeted high-dose nutrient therapy.

Identifiers

PMID31043911
PMCPMC6469460
OpenAlexW3004558737

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.