Evidence map›Paper›PMID 31043811›Full record

ArticleCurrent oncology (Toronto, Ont.)2019

Cost-of-illness study for non-small-cell lung cancer using real-world data.

S J Seung, M Hurry, S Hassan, R N Walton, W K Evans

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Efficacy and cost-effectiveness of lung cancer screening in France with low-dose computed tomography.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026
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  18. A cost-utility analysis of the impact of electronic nicotine delivery systems on health care costs and outcomes in Canada.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

S J Seunghope Research Centre, Sunnybrook Research Institute, Toronto, ON.
M HurryAstraZeneca Canada, Mississauga, ON.
S Hassanhope Research Centre, Sunnybrook Research Institute, Toronto, ON.
R N WaltonAstraZeneca Canada, Mississauga, ON.
W K EvansMcMaster University, Hamilton, ON.
AstraZeneca (Canada) · CASunnybrook Health Science Centre · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With recent advances in the treatment of non-small-cell lung cancer (nsclc) and current fiscal constraints within publicly funded health care systems, understanding the real-world economic effect of lung cancer management has become important. The objective of the present study was to determine the costs and resources used in the management of nsclc cohorts in Ontario. Methods: Patients diagnosed between 1 April 2010 and 31 March 2015 were identified in the Ontario Cancer Registry and linked to provincial administrative databases, capturing resources such as hospitalizations, cancer clinic visits, physician services, and systemic therapies or radiotherapy. A cost-of-illness analysis using a bottom-up approach and the GETCOST macro available at ices determined the overall total and mean costs in 2017 Canadian dollars. Resource utilization results were analyzed according to the total number of encounters per resource, the number of patients using each resource, and the number of encounters per patient. A separate cost-and-resource analysis was conducted for radiotherapy. Results: The 24,729 nsclc patients identified included 4542 with stage iii unresectable disease and 10,103 with stage iv nonsquamous disease. The overall total cost for all nsclc patients was $1.9 billion, with inpatient hospitalizations ($635.2 million), cancer clinic visits ($323.7 million), and physician services ($301.4 million) being the top cost contributors. The mean cost per patient was $76,816. The total cost of radiotherapy was $38.5 million. Conclusions: Real-world costs for the management of nsclc during the 5-year period examined were substantial, despite the fact that median survival was poor and treatment information was limited.

Indexed as

Health Care CostsAgedCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsMaleMiddle Agedadministrative datacostsLung cancerOntarioresource utilization

Identifiers

PMID31043811
PMCPMC6476449
OpenAlexW2943072932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.