Evidence map›Paper›PMID 31043759›Full record

ArticleNature genetics2019

Exome sequencing highlights the role of wild-relative introgression in shaping the adaptive landscape of the wheat genome.

Fei He, Raj Pasam, Fan Shi, Surya Kant, Gabriel Keeble-Gagnere, Pippa Kay, Kerrie Forrest, Allan Fritz, Pierre Hucl, Krystalee Wiebe and 13 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 192 papers.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

192 citing papers in PubMed.

  1. Article
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  9. Genomic diversity and the domestication history of cotton (Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
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  12. Article
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  15. Review
  16. Article
  17. Genetic origins and climate-induced erosion in economically important Asian walnuts.Conservation biology : the journal of the Society for Conservation Biology · 2026
    Article
  18. Article
  19. Article
  20. Unlocking the genetic potential ofFrontiers in plant science · 2026
    Review

132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Fei HeDepartment of Plant Pathology, Kansas State University, Manhattan, KS, USA.
Raj PasamAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.ORCID http://orcid.org/0000-0003-0908-1882
Fan ShiAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Surya KantAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Gabriel Keeble-GagnereAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Pippa KayAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Kerrie ForrestAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Allan FritzDepartment of Agronomy, Kansas State University, Manhattan, KS, USA.
Pierre HuclCrop Development Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Krystalee WiebeCrop Development Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Ron KnoxSwift Current Research and Development Centre, Swift Current, Saskatchewan, Canada.ORCID http://orcid.org/0000-0002-2030-3899
Richard CuthbertSwift Current Research and Development Centre, Swift Current, Saskatchewan, Canada.
Curtis PozniakCrop Development Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID http://orcid.org/0000-0002-7536-3856
Alina AkhunovaDepartment of Plant Pathology, Kansas State University, Manhattan, KS, USA.ORCID http://orcid.org/0000-0002-2714-3525
Peter L MorrellDepartment of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN, USA.
John P DaviesCorteva Agriscience, Agriculture Division of DowDuPont, Indianapolis, IN, USA.
Steve R WebbCorteva Agriscience, Agriculture Division of DowDuPont, Indianapolis, IN, USA.
German SpangenbergAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Ben HayesAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.ORCID http://orcid.org/0000-0002-5606-3970
Hans DaetwylerAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Josquin TibbitsAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Matthew HaydenAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia. matthew.hayden@ecodev.vic.gov.au.ORCID http://orcid.org/0000-0003-3117-5500
Eduard AkhunovDepartment of Plant Pathology, Kansas State University, Manhattan, KS, USA. eakhunov@ksu.edu.ORCID http://orcid.org/0000-0002-0416-5211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introgression is a potential source of beneficial genetic diversity. The contribution of introgression to adaptive evolution and improvement of wheat as it was disseminated worldwide remains unknown. We used targeted re-sequencing of 890 diverse accessions of hexaploid and tetraploid wheat to identify wild-relative introgression. Introgression, and selection for improvement and environmental adaptation, each reduced deleterious allele burden. Introgression increased diversity genome wide and in regions harboring major agronomic genes, and contributed alleles explaining a substantial proportion of phenotypic variation. These results suggest that historic gene flow from wild relatives made a substantial contribution to the adaptive diversity of modern bread wheat.

Indexed as

AcclimatizationDomesticationEvolution, MolecularExome SequencingGene FlowGenetic VariationGenome, PlantPhenotypePlant BreedingPolymorphism, Single NucleotidePolyploidyTetraploidyTriticum

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.