Evidence map›Paper›PMID 31043737›Full record

ArticleNature2019

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Brandon Faubert, Divya Bezwada, Jaime Rodriguez-Canales, Pamela Villalobos, Yu-Fen Lin and 16 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors.

Jiyeon KimChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Zeping HuChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Ling CaiChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Kailong LiChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Eunhee ChoiDepartment of Pharmacology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Brandon FaubertChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Divya BezwadaChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Jaime Rodriguez-CanalesDepartment of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, 2130 West Holcombe Boulevard, Houston, Texas, 77030, USA.
Pamela VillalobosDepartment of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, 2130 West Holcombe Boulevard, Houston, Texas, 77030, USA.
Yu-Fen LinDepartment of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Min NiChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Kenneth E HuffmanHamon Center for Therapeutic Oncology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Luc GirardHamon Center for Therapeutic Oncology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Lauren A ByersDepartment of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, 2130 West Holcombe Boulevard, Houston, Texas, 77030, USA.
Keziban Unsal-KacmazOncology Research Unit, Pfizer, 401 North Middletown Road, Pearl River, New York, 10965, USA.
Christopher G PeñaDepartment of Pathology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
John V HeymachDepartment of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, 2130 West Holcombe Boulevard, Houston, Texas, 77030, USA.
Els WautersRespiratory Division, University of Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Johan VansteenkisteRespiratory Division, University of Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Diego H CastrillonDepartment of Pathology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Benjamin P C ChenDepartment of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Ignacio WistubaDepartment of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, 2130 West Holcombe Boulevard, Houston, Texas, 77030, USA.
Diether LambrechtsLaboratory for Translational Genetics, Department of Human Genetics, KU Leuven, O&N 4 Herestraat 49 - box 912, 3000, Leuven, Belgium.
Jian XuChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
John D MinnaHamon Center for Therapeutic Oncology, UT Southwestern Medical Center, Dallas, Texas, 75390, USA.
Ralph J DeBerardinisChildren's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas, 75390, USA. Ralph.Deberardinis@UTSouthwestern.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Further analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.

Identifiers

PMID31043737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.