Evidence map›Paper›PMID 31043703›Full record

ArticleScientific reports2019

Vision-related quality of life and symptom perception change over time in newly-diagnosed primary open angle glaucoma patients.

Ivano Riva, Lorenzo Legramandi, Eliana Rulli, Anastasios G Konstas, Andreas Katsanos, Francesco Oddone, Robert N Weinreb, Luciano Quaranta, Italian Study Group on QoL in Glaucoma

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Quality of Life in Patients with Posterior Segment Eye Diseases.Journal of ophthalmic & vision research · 2026
    Review
  2. Article
  3. Article
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  5. Review
  6. Article
  7. Article
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  10. Review
  11. Article
  12. Review
  13. Article
  14. Seeing through the patient's Eyes: Exploring quality of life in glaucoma patients.Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ivano RivaIRCCS - Fondazione Bietti, Rome, Italy.ORCID http://orcid.org/0000-0002-7397-2260
Lorenzo LegramandiIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Eliana RulliIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.ORCID http://orcid.org/0000-0003-1058-4137
Anastasios G Konstas1st University Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Andreas KatsanosDepartment of Ophthalmology, University of Ioannina, Ioannina, Greece.
Francesco OddoneIRCCS - Fondazione Bietti, Rome, Italy.
Robert N WeinrebHamilton Glaucoma Center, Shiley Eye Institute, and the Department of Ophthalmology, University of California San Diego, San Diego, USA.
Luciano QuarantaDepartment of Surgical & Clinical, Diagnostic and Pediatric Sciences, Section of Ophthalmology, University of Pavia - IRCCS Fondazione Policlinico, San Matteo, Pavia, Italy. luciano.quaranta@unipv.it.
Italian Study Group on QoL in Glaucoma

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the change over time of vision-related quality of life (QoL) and glaucoma symptoms in a population of newly-diagnosed primary open angle glaucoma (POAG) patients. Multicenter, prospective study. Consecutive newly-diagnosed POAG patients were enrolled and followed-up for one year. Follow-up visits were scheduled at 6 and 12 months from baseline. At each visit, vision-related QoL and glaucoma-related symptoms were assessed by the means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and the Glaucoma Symptom Scale (GSS), respectively. Trends over time for NEI-VFQ-25 and GSS scores were evaluated with longitudinal linear mixed models. One-hundred seventy-eight patients were included in the analysis. At baseline, early to moderate glaucoma stages were associated with higher scores for most GSS and NEI-VFQ-25 items, while lower best-corrected visual acuity was associated with lower scores for 4 of the 12 NEI-VFQ-25 items. During the follow-up, all the GSS scores, the NEI-VFQ-25 total score, and 7 of the 12 NEI-VFQ-25 scores significantly improved (p < 0.05). In multivariate model, higher increases of most GSS and NEI-VFQ-25 scores were modeled in patients with low scores at baseline. Vision-related QoL and glaucoma-related symptom perception significantly improved during the one-year follow-up in this population of newly diagnosed POAG patients.

Identifiers

PMID31043703
PMCPMC6494828

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.