ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Increased Neural Activity in Mesostriatal Regions after Prefrontal Transcranial Direct Current Stimulation and l-DOPA Administration.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Comparative efficacy of neuromodulation techniques for Alzheimer's disease: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in neuroscience · 2026Pooled it
- Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating.Cognitive, affective & behavioral neuroscience · 2020Trial
- The Effectiveness of Transcranial Direct Current Stimulation (tDCS) in Improving Performance in Soccer Players-A Scoping Review.Journal of clinical medicine · 2026Review
- Multimodal neuroimaging reveals brain neurochemical disturbances associated with superoxide dismutase in first-episode drug-naïve schizophrenia.Translational psychiatry · 2026Article
- An examination of the influence of prefrontal cortical brain stimulation on sexual decision making.Oxford open neuroscience · 2026Article
- Modulation of reward positivity and blink rate in children with attention deficit hyperactivity disorder (ADHD) during and following transcranial direct current stimulation.Translational psychiatry · 2025Article
- Resting-State Activity Changes Induced by tDCS in MS Patients and Healthy Controls: A Simultaneous tDCS rs-fMRI Study.Bioengineering (Basel, Switzerland) · 2025Article
- Repetitive prefrontal tDCS activates VTA dopaminergic neurons, resulting in attenuation of Alzheimer's Disease-like deficits in Tg2576 mice.Alzheimer's research & therapy · 2025Article
- Research progress of tDCS in the treatment of ADHD.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Dopamine Alters the Effect of Brain Stimulation on Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Transcranial direct current stimulation for post-COVID fatigue: a randomized, double-blind, controlled pilot study.Brain communications · 2023Article
- Cerebral metabolic rate of oxygen (CMROBrain research · 2022Article
- High-Frequency Transcranial Random Noise Stimulation over the Left Prefrontal Cortex Increases Resting-State EEG Frontal Alpha Asymmetry in Patients with Schizophrenia.Journal of personalized medicine · 2022Article
- Distinguishing the Roles of the Dorsomedial Prefrontal Cortex and Right Temporoparietal Junction in Altruism in Situations of Inequality: A Transcranial Direct Current Stimulation Study.Frontiers in human neuroscience · 2022Article
- Distinct role of the right temporoparietal junction in advantageous and disadvantageous inequity: A tDCS study.Frontiers in behavioral neuroscience · 2022Article
- Inverse Association Between Resting-State Putamen Activity and Iowa Gambling Task Performance in Patients With Obsessive-Compulsive Disorder and Control Subjects.Frontiers in psychiatry · 2022Article
- Altered Brain Activity in Depression of Parkinson's Disease: A Meta-Analysis and Validation Study.Frontiers in aging neuroscience · 2022Article
- Review
- Long-term effects of intermittent early life stress on primate prefrontal-subcortical functional connectivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Preliminary effects of prefrontal tDCS on dopamine-mediated behavior and psychophysiology.Behavioural brain research · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dopamine dysfunction is associated with a wide range of neuropsychiatric disorders commonly treated pharmacologically or invasively. Recent studies provide evidence for a nonpharmacological and noninvasive alternative that allows similar manipulation of the dopaminergic system: transcranial direct current stimulation (tDCS). In rodents, tDCS has been shown to increase neural activity in subcortical parts of the dopaminergic system, and recent studies in humans provide evidence that tDCS over prefrontal regions induces striatal dopamine release and affects reward-related behavior. Based on these findings, we used fMRI in healthy human participants and measured the fractional amplitude of low-frequency fluctuations to assess spontaneous neural activity strength in regions of the mesostriatal dopamine system before and after tDCS over prefrontal regions (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.