Evidence map›Paper›PMID 31043480›Full record

ArticleThe Journal of biological chemistry2019

Tyrosine aminotransferase is involved in the oxidative stress response by metabolizing

Brett R Ipson, Rebecca A Green, John T Wilson, Jacob N Watson, Kym F Faull, Alfred L Fisher

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Insights into the Role ofInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Repeated exposure to eucalyptus wood smoke alters pulmonary gene and metabolic profiles in male Long-Evans rats.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in microbiology · 2023
    Article
  10. Article
  11. Oxidative medicine and cellular longevity · 2022
    Article
  12. Article
  13. Toxicity ofPlants (Basel, Switzerland) · 2021
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brett R IpsonFrom the Department of Cell Systems and Anatomy.
Rebecca A Greenthe Ludwig Institute for Cancer Research, San Diego, La Jolla, California 92093.
John T Wilsonthe Center for Healthy Aging, and.
Jacob N Watsonthe Center for Healthy Aging, and.
Kym F Faullthe Pasarow Mass Spectrometry Laboratory, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, UCLA, Los Angeles, California 90095, and.
Alfred L Fisherthe Center for Healthy Aging, and alfred.fisher@unmc.edu.ORCID 0000-0001-6451-2644

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
TRANSGENIC COREP30AG013319 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI JAMES FLOYD NELSON · 1995 to 2026
$30.6M
Effects of insulin-like signaling, aging, and ubiquinone on C. elegans muscleR01AG044768 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FISHER, ALFRED L · 2012 to 2016
$1.6M
South Texas Medical Scientist Training Program (STX-MSTP)T32GM113896 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CAVAZOS, JOSE E · 2018 to 2022
$1.1M
Regulation on of the AIRAP/aip-1 pathway by metabolic stressR01ES017761 · NIEHS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FISHER, ALFRED L · 2010 to 2014
$1.1M
High Throughput DNA Sequencer: Illumina HiSeq 3000 SequencerS10OD021805 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2016 to 2016
$600k
Improving omega-3 fatty acid supplementation with microencapsulationR21NS102782 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FISHER, ALFRED L · 2018 to 2019
$480k
Contribution of m-tyrosine to the adverse effects of oxidative stressF30AG053034 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI IPSON, BRETT · 2016 to 2019
$151k
NCI NIH HHS P30 CA054174NIA NIH HHS F30 AG053034NIA NIH HHS P30 AG013319NIA NIH HHS R01 AG044768NIEHS NIH HHS R01 ES017761NIGMS NIH HHS T32 GM113896NIH HHS S10 OD021805NINDS NIH HHS R21 NS102782
6 · The paper itself

Abstract

Under oxidative stress conditions, hydroxyl radicals can oxidize the phenyl ring of phenylalanine, producing the abnormal tyrosine isomer

Indexed as

Gene Expression RegulationOxidative StressAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA-Binding ProteinsLongevityMutationOxidation-ReductionTranscription FactorsTyrosineTyrosine Transaminase3-tyrosineCaenorhabditis elegans ProteinsDNA-Binding Proteinsskn-1 protein, C eleganstatn-1 protein, C elegansTranscription FactorsTyrosineTyrosine Transaminaseagingamino acidF01D4.5gene expressionmetabolismmeta-tyrosineNrf2oxidative stressreactive oxygen speciesribosomeSKN-1transcriptional regulationtyrosinetyrosine aminotransferase

Identifiers

PMID31043480
PMCPMC6579467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.