Evidence map›Paper›PMID 31043171›Full record

ArticleBMC neurology2019

18F-FDG PET/CT: an unexpected case of Huntington's disease.

Sebastian Michels, Hans-Georg Buchholz, Florian Rosar, Isabel Heinrich, Manuela A Hoffmann, Susann Schweiger, Oliver Tüscher, Mathias Schreckenberger

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. A Case of Late-Onset De Novo Huntington's Disease Diagnosed viaDementia and neurocognitive disorders · 2024
    Article
  4. Review
  5. Increased [Journal of neurotrauma · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sebastian MichelsDepartment of Nuclear Medicine, University Medical Center of Johannes Gutenberg-University, Mainz, Germany. Sebastian.Michels@rku.de.ORCID http://orcid.org/0000-0002-9265-9034
Hans-Georg BuchholzDepartment of Nuclear Medicine, University Medical Center of Johannes Gutenberg-University, Mainz, Germany.
Florian RosarDepartment of Nuclear Medicine, University Medical Center of Johannes Gutenberg-University, Mainz, Germany.
Isabel HeinrichDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Manuela A HoffmannDepartment of Nuclear Medicine, University Medical Center of Johannes Gutenberg-University, Mainz, Germany.
Susann SchweigerDepartment of Human Genetics, University Medical Center of Johannes Gutenberg-University, Mainz, Germany.
Oliver TüscherDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Mathias SchreckenbergerDepartment of Nuclear Medicine, University Medical Center of Johannes Gutenberg-University, Mainz, Germany.
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuntington's disease (HD) is a rare, genetic neurodegenerative disorder often presenting with emotional, cognitive and behavioral abnormalities before manifestation of disease defining motor symptoms. Cognitive impairment is a frequent clinical feature caused by different dementia subtypes. Imaging cortical and subcortical glucose metabolism via CASE PRESENTATION: The patient is a 54-year old man presenting with progressive cognitive impairment and mild orofacial dyskinesia.

conclusionsHuntington's disease is a rare but important differential diagnosis of cognitive impairment, especially before motor symptoms are manifest.

Indexed as

BrainFluorodeoxyglucose F18HumansHuntington DiseaseMaleMiddle AgedPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18FDG-PET/CTHuntington’s diseaseStriatal hypometabolism

Identifiers

PMID31043171
PMCPMC6495557
OpenAlexW2946848311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.