Evidence map›Paper›PMID 31042714›Full record

ArticlePloS one2019

Adherence to the iDSI reference case among published cost-per-DALY averted studies.

Joanna Emerson, Ari Panzer, Joshua T Cohen, Kalipso Chalkidou, Yot Teerawattananon, Mark Sculpher, Thomas Wilkinson, Damian Walker, Peter J Neumann, David D Kim

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joanna EmersonCenter for the Evaluation of Value and Risk in Health, Tufts Medical Center, Boston, MA, United States of America.ORCID 0000-0002-1199-582X
Ari PanzerCenter for the Evaluation of Value and Risk in Health, Tufts Medical Center, Boston, MA, United States of America.
Joshua T CohenCenter for the Evaluation of Value and Risk in Health, Tufts Medical Center, Boston, MA, United States of America.
Kalipso ChalkidouInstitute of Global Health Innovation, Imperial College London, London, United Kingdom.
Yot TeerawattananonThe Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Mark SculpherCentre for Health Economics, University of York, York, United Kingdom.ORCID 0000-0003-3746-9913
Thomas WilkinsonHealth Economics Unit, School of Public Health and Family Medicine, University of Cape Town, South Africa.
Damian WalkerBill & Melinda Gates Foundation, Seattle, WA, United States of America.
Peter J NeumannCenter for the Evaluation of Value and Risk in Health, Tufts Medical Center, Boston, MA, United States of America.
David D KimCenter for the Evaluation of Value and Risk in Health, Tufts Medical Center, Boston, MA, United States of America.

Funding

Medical Research Council MR/R015600/1
6 · The paper itself

Abstract

backgroundThe iDSI reference case, originally published in 2014, aims to improve the quality and comparability of cost-effectiveness analyses (CEA). This study assesses whether the development of the guideline is associated with an improvement in methodological and reporting practices for CEAs using disability-adjusted life-years (DALYs).

methodsWe analyzed the Tufts Medical Center Global Health CEA Registry to identify cost-per-DALY averted studies published from 2011 to 2017. Among each of 11 principles in the iDSI reference case, we translated all methodological specifications and reporting standards into a series of binary questions (satisfied or not satisfied) and awarded articles one point for each item satisfied. We then calculated methodological and reporting adherence scores separately as a percentage of total possible points, measured as normalized adherence score (0% = no adherence; 100% = full adherence). Using the year 2014 as the dissemination period, we conducted a pre-post analysis. We also conducted sensitivity analyses using: 1) optional criteria in scoring, 2) alternate dissemination period (2014-2015), and 3) alternative comparator classification.

resultsArticles averaged 60% adherence to methodological specifications and 74% adherence to reporting standards. While methodological adherence scores did not significantly improve (59% pre-2014 vs. 60% post-2014, p = 0.53), reporting adherence scores increased slightly over time (72% pre-2014 vs. 75% post-2014, p<0.01). Overall, reporting adherence scores exceeded methodological adherence scores (74% vs. 60%, p<0.001). Articles seldom addressed budget impact (9% reporting, 10% methodological) or equity (7% reporting, 7% methodological).

conclusionsThe iDSI reference case has substantial potential to serve as a useful resource for researchers and policy-makers in global health settings, but greater effort to promote adherence and awareness is needed to achieve its potential.

Indexed as

Global HealthCost-Benefit AnalysisQuality-Adjusted Life Years

Identifiers

PMID31042714
PMCPMC6493721

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.