ArticlePsychiatry investigation2019
Comparison of the Usefulness of the PHQ-8 and PHQ-9 for Screening for Major Depressive Disorder: Analysis of Psychiatric Outpatient Data.
Article in Psychiatry investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 140 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
140 citing papers in PubMed, 1 synthesis or guideline pooled it, 265 citations in OpenAlex.
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- Association between problematic internet use and depressive symptoms among individuals at high-risk of cannabis use disorder: a cross-sectional study in Quebec (Canada).Addictive behaviors reports · 2026Article
- An examination of chronotype associations with symptoms of depression, PTSD, and sleep disturbances in US military veterans.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Leveraging machine learning to personalize depression treatment: A pre-registered study of 828 adults randomized to a digital single-session intervention or waitlist.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Depressive symptoms and perceived stress in patients with head and neck cancer undergoing intensity-modulated radiation therapy: A longitudinal study.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2026Article
- Longitudinal coupling of obsessive-compulsive symptoms with depressive and anxiety symptoms: A cross-domain latent growth curve analysis.Journal of mood and anxiety disorders · 2026Article
- Feasibility and preliminary outcomes of a school-based mental health program: evaluation of socio-emotional skills training component in the Colombian Amazon.Scientific reports · 2026Article
- Screening Emotions in Adolescents Receiving Care at the Hospital for mild Traumatic Brain Injury (SEARCH-mTBI): protocol for a multicenter observational study.BMC pediatrics · 2026Article
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- Burnout and Depression of Medical Faculty: After Mass Resignation of Junior Doctors in Korea.Journal of Korean medical science · 2026Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThis study aimed to demonstrate that the Patient Health Questionnaire (PHQ)-8 is not less useful than the PHQ-9 as a screening test for major depressive disorder (MDD).
methodsWe performed a retrospective analysis of 567 patients in psychiatric outpatient units. The Mini International Neuropsychiatric Interview was used to diagnose MDD. We derived the validity and reliability of the PHQ-8 and PHQ-9. To evaluate the ability of the PHQ-8 and PHQ-9 to discriminate MDD, we drew receiver operating characteristic (ROC) curves and compared the areas under the curves (AUCs).
resultsOf the 567 participants, 207 (36.5%) were diagnosed with MDD. Cronbach's αs for the PHQ-8 and PHQ-9 were 0.892 and 0.876, respectively. Similar to the PHQ-9, the PHQ-8 was also associated with scores on the Hamilton Depression Rating Scale in a correlation analysis. When we drew ROC curves for the PHQ-8 and PHQ-9, there was no statistically significant difference in the AUCs. With a cutoff score of 10, the PHQ-8 showed a sensitivity of 58.3%, specificity of 83.1%, positive predictive value of 53.4%, and negative predictive value of 85.7%.
conclusionIn a psychiatric outpatient sample, the PHQ-8 was as useful as the PHQ-9 for MDD screening.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.