Evidence map›Paper›PMID 31042423›Full record

ReviewAmerican journal of physiology. Cell physiology2019

Long noncoding RNAs in intestinal epithelium homeostasis.

Lan Xiao, Myriam Gorospe, Jian-Ying Wang

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 34 citations in OpenAlex.

  1. Long Noncoding RNANon-coding RNA · 2026
    Article
  2. Novel role of the lncRNA EPR as oncosuppressor in intestinal cancer.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
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  10. Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders.Journal of investigative surgery : the official journal of the Academy of Surgical Research · 2024
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lan XiaoCell Biology Group, Department of Surgery, University of Maryland School of Medicine , Baltimore, Maryland.
Myriam GorospeLaboratory of Genetics and Genomics, National Institute on Aging-Intramural Research Program, National Institutes of Health , Baltimore, Maryland.
Jian-Ying WangCell Biology Group, Department of Surgery, University of Maryland School of Medicine , Baltimore, Maryland.
University of Maryland, Baltimore · USNational Institutes of Health · US

Funding

Intestinal Mucosal Growth in Health & Surgical DiseasesR01DK057819 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI Jian-Ying Wang · 2000 to 2026
$7.4M
Surgical Studies of Gut PermeabilityR01DK068491 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI Jian-Ying Wang · 2004 to 2026
$7.0M
Mucosal Repair in Gut Surgical DisordersR01DK061972 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI WANG, JIAN-YING · 2002 to 2023
$6.7M
REGULATION OF INTESTINAL EPITHELIAL RESTITUTIONI01BX000332 · VA · BALTIMORE VA MEDICAL CENTER · PI Jian-Ying Wang · 2009 to 2026
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BLRD Research Career Scientist Award ApplicationIK6BX004213 · VA · BALTIMORE VA MEDICAL CENTER · PI WANG, JIAN-YING · 2018 to 2025
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BLRD VA I01 BX000332BLRD VA IK6 BX004213NIDDK NIH HHS R01 DK057819NIDDK NIH HHS R01 DK061972
6 · The paper itself

Abstract

The epithelium of the mammalian intestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through well-controlled mechanisms. Long noncoding RNAs (lncRNAs) regulate a variety of biological functions and are intimately involved in the pathogenesis of diverse human diseases. Here we highlight the roles of several lncRNAs expressed in the intestinal epithelium, including

Indexed as

Cell ProliferationIntestinal AbsorptionRegenerationAnimalsEpithelial CellsGene Expression RegulationHomeostasisHumansIntestinal MucosaPermeabilityRNA, Long NoncodingSignal TransductionRNA, Long Noncodinggut permeabilityintestinal mucosal renewalmicroRNAposttranscriptional regulationRNA-binding proteins

Identifiers

PMID31042423
PMCPMC6689755
OpenAlexW2943504396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.