Evidence map›Paper›PMID 31042404›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle.

Tonio Pera, Eric Tompkins, Michael Katz, Bin Wang, Deepak A Deshpande, Edward J Weinman, Raymond B Penn

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. NaJournal of immunology (Baltimore, Md. : 1950) · 2021
    Article
  6. Article
  7. Article
  8. Effects of ATP-competitive and function-selective ERK inhibitors on airway smooth muscle cell proliferation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tonio PeraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Eric TompkinsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Michael KatzDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Bin WangDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Deepak A DeshpandeDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Edward J WeinmanDepartment of Medicine, University of Maryland, Baltimore, Maryland, USA.
Raymond B PennDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Thomas Jefferson University · USUniversity of Maryland, Baltimore · US

Funding

G Protein-Coupled Receptor Signaling in Airway Smooth MuR01HL058506 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RAYMOND B. PENN · 2001 to 2026
$9.3M
Biased Muscarinic Acetylcholine Receptor Signaling in Obstructive Lung Disease Pathology and TherapyR01HL140064 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI Tonio Pera · 2018 to 2026
$3.1M
Optimizing EP receptor subtype targeting for asthma therapyR01HL136209 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI BIRRELL, MARK A, BOYCE, JOSHUA A · 2017 to 2020
$2.2M
Functional Diversity of Compartmentalized Calcium Signaling in Airway Smooth MuscleR01HL137030 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI DESHPANDE, DEEPAK A · 2018 to 2021
$2.2M
BETA ADRENERGIC RECEPTOR REGULATION IN HUMAN AIRWAY MUSCR29HL058506 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI PENN, RAYMOND B. · 1997 to 2000
$113k
NHLBI NIH HHS R01 HL058506NHLBI NIH HHS R01 HL136209NHLBI NIH HHS R01 HL137030NHLBI NIH HHS R01 HL140064NHLBI NIH HHS R29 HL058506
6 · The paper itself

Abstract

Na

Indexed as

CCAAT-Enhancer-Binding Protein-betaCyclic AMPCyclin D1Cystic Fibrosis Transmembrane Conductance RegulatorGene Expression RegulationGene Knockdown TechniquesHumansMuscle, SmoothPhosphoproteinsReceptors, G-Protein-CoupledRespiratory Physiological PhenomenaRespiratory SystemSignal TransductionSodium-Hydrogen ExchangersCCAAT-Enhancer-Binding Protein-betaCCND1 protein, humanCFTR protein, humanCyclic AMPCyclin D1Cystic Fibrosis Transmembrane Conductance RegulatorPhosphoproteinsReceptors, G-Protein-Coupledsodium-hydrogen exchanger regulatory factorSodium-Hydrogen Exchangersasthmac/EBPcompartmentalized signalingEBP50PKA

Identifiers

PMID31042404
PMCPMC6662985
OpenAlexW2942907696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.