Evidence map›Paper›PMID 31042345›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2019

The Role of the Local Bone Marrow Renin-Angiotensin System in Multiple Myeloma

Bülent Saka, Müge Sayitoğlu, Zülal İstemihan, M. Akif Karan, Nilgün Erten, Öner Doğan, Uğur Özbek, Sema Genç, Cemil Taşçıoğlu, Sevgi Kalayoğlu-Beşışık

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. The impact of STAiR18 on multiple myeloma survival rates.Journal of translational medicine · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. COVID-19, Renin-Angiotensin System, and HematopoiesisTurkish journal of haematology : official journal of Turkish Society of Haematology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bülent Sakaİstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, TurkeyORCID 0000-0001-5404-5579
Müge Sayitoğluİstanbul University, Aziz Sancar Institute of Experimental Research, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-8648-213X
Zülal İstemihanİstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, TurkeyORCID 0000-0003-2961-2660
M. Akif Karanİstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, TurkeyORCID 0000-0002-9080-404X
Nilgün Ertenİstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, TurkeyORCID 0000-0002-1113-9310
Öner Doğanİstanbul University, İstanbul Faculty of Medicine, Department of Pathology, İstanbul, Turkey
Uğur Özbekİstanbul University, Aziz Sancar Institute of Experimental Research, Department of Genetics, İstanbul, Turkey
Sema Gençİstanbul University, İstanbul Faculty of Medicine, Department of Biochemistry, İstanbul, TurkeyORCID 0000-0002-2577-9263
Cemil Taşçıoğluİstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, TurkeyORCID 0000-0003-3808-6957
Sevgi Kalayoğlu-Beşışıkİstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, TurkeyORCID 0000-0001-8095-5445
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Angiotensin II promotes growth and angiogenesis via type 1 receptors (AGTR1) in certain tumors. In this study, we examine the bone marrow AGTR1 expression in multiple myeloma (MM) and its relationship with the regulation of angiogenesis and prognostic factors. Materials and Methods: Bone marrow Results: Bone marrow samples of the patients showed increased VEGF, fVIIIrAg, and CD34 staining and higher Conclusion:

Indexed as

AdultAgedAged, 80 and overBone MarrowFemaleHumansMaleMiddle AgedMultiple MyelomaRenin-Angiotensin SystemAngiotensin type 1a receptorMultiple myelomaRenin-angiotensin system

Identifiers

PMID31042345
PMCPMC6682785
OpenAlexW2941133858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.