Evidence map›Paper›PMID 31042301›Full record

Trial reportJournal of orthopaedic research : official publication of the Orthopaedic Research Society2019

Gait Mechanics in Women of the ACL-SPORTS Randomized Control Trial: Interlimb Symmetry Improves Over Time Regardless of Treatment Group.

Jacob J Capin, Ryan Zarzycki, Naoaki Ito, Ashutosh Khandha, Celeste Dix, Kurt Manal, Thomas S Buchanan, Lynn Snyder-Mackler

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. [Three-dimensional kinematic analysis of knee joint after anterior cruciate ligament reconstruction with personalized femoral positioner based on apex of deep cartilage].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Preoperative and Post-Rehabilitation Predictors of Gait Biomechanics Six Months After Total Knee Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Secondary Anterior Cruciate Ligament Injury Prevention Training in Athletes: What Is the Missing Link?International journal of environmental research and public health · 2023
    Review
  16. Males and females have different muscle activity patterns during gait after ACL injury and reconstruction.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2022
    Article
  17. Knee joint biomechanics during gait improve from 3 to 6 months after anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jacob J CapinBiomechanics and Movement Science Program, University of Delaware, Newark, Delaware.ORCID 0000-0001-9361-3700
Ryan ZarzyckiDepartment of Physical Therapy, Arcadia University, Glenside, Pennsylvania.
Naoaki ItoDepartment of Physical Therapy, University of Delaware, Newark, Delaware.
Ashutosh KhandhaDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.ORCID 0000-0001-6003-3881
Celeste DixBiomechanics and Movement Science Program, University of Delaware, Newark, Delaware.
Kurt ManalBiomechanics and Movement Science Program, University of Delaware, Newark, Delaware.
Thomas S BuchananDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.
Lynn Snyder-MacklerBiomechanics and Movement Science Program, University of Delaware, Newark, Delaware.
University of Delaware · USKessler Institute for Rehabilitation · USArcadia University · US

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
Dynamic Stability in the ACL Injured KneeR37HD037985 · NICHD · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2012 to 2021
$4.2M
PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
CAN NEUROMUSCULAR TRAINING ALTER MOVEMENT PATTERNS?R01AR048212 · NIAMS · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2005 to 2015
$3.6M
ACL Reconstructed Knee: qMRI and Biomechanical ModelingR01HD087459 · NICHD · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2016 to 2020
$1.8M
Walking Mechanics, Early Osteoarthritis Development, and Neuromuscular Training after Traumatic Knee InjuryF30HD096830 · NICHD · UNIVERSITY OF DELAWARE · PI CAPIN, JACOB J · 2018 to 2019
$53k
Eunice Kennedy Shriver National Institute of Child Health and Human Development F30-HD096830Eunice Kennedy Shriver National Institute of Child Health and Human Development R01-AR048212Eunice Kennedy Shriver National Institute of Child Health and Human Development R01-HD087459Foundation for Physical Therapy Promotion of Doctoral Studies (PODS) - Level II ScFoundation for Physical Therapy Promotion of Doctoral Studies (PODS) - Level I SchNIAMS NIH HHS R01 AR048212NICHD NIH HHS F30 HD096830NICHD NIH HHS R01 HD087459NICHD NIH HHS R37 HD037985NICHD NIH HHS T32 HD007490NIGMS NIH HHS U54 GM104941NIGMS NIH HHS U54-GM104941University of Delaware University Dissertation Fellowship Award (JJC)University of Delaware University Doctoral Fellowship Award (JJC)
6 · The paper itself

Abstract

Women after anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR) are more likely than men to exhibit asymmetric movement patterns, which are associated with post-traumatic osteoarthritis. We developed the ACL specialized post-operative return-to-sports (ACL-SPORTS) randomized control trial to test the effect of strength, agility, plyometric, and secondary prevention (SAPP) training with and without perturbation training (SAPP + PERT) on gait mechanics in women after ACLR. We hypothesized that movement symmetry would improve over time across both groups but more so among the SAPP + PERT group. Thirty-nine female athletes 3-9 months after primary ACLR were randomized to SAPP or SAPP + PERT training. Biomechanical testing during overground walking occurred before (Pre-training) and after (Post-training) training and one and 2 years post-operatively. Hip and knee kinematic and kinetic variables were compared using repeated measures analysis of variance with Bonferroni corrections for post hoc comparisons (α = 0.05). There was a time by limb interaction effect (p = 0.028) for peak knee flexion angle (PKFA), the primary outcome which powered the study, characterized by smaller PKFA in the involved compared to uninvolved limbs across treatment groups at Pre-training, Post-training, and 1 year, but not 2 years. Similar findings occurred across sagittal plane knee excursions and kinetics and hip extension excursion at midstance. There were no meaningful interactions involving group. Neither SAPP nor SAPP + PERT training improved walking mechanics, which persisted 1 but not 2 years after ACLR. Statement of clinical significance: Asymmetrical movement patterns persisted long after participants achieved symmetrical strength and functional performance, suggesting more time is needed to recover fully after ACLR. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1743-1753, 2019.

Indexed as

GaitAdolescentAdultAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaExercise TherapyFemaleHumansKnee JointProspective StudiesReturn to SportSecondary PreventionYoung AdultACL-SPORTS traininganterior cruciate ligament reconstruction (ACLR)gait mechanicsmusculoskeletal modelingwomen

Identifiers

PMID31042301
PMCPMC6824924
OpenAlexW2942742427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.