Evidence map›Paper›PMID 31042288›Full record

ArticleThe Journal of clinical endocrinology and metabolism2019

Association of Glucose Concentrations at Hospital Discharge With Readmissions and Mortality: A Nationwide Cohort Study.

Elias K Spanakis, Guillermo E Umpierrez, Tariq Siddiqui, Min Zhan, Soren Snitker, Jeffrey C Fink, John D Sorkin

Abstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Hospital Diabetes Meeting 2022.Journal of diabetes science and technology · 2022
    Article
  12. Observational
  13. Review
  14. Patient Understanding of Discharge Instructions for Home Diabetes Self-Management and Risk for Hospital Readmission and Emergency Department Visits.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Hospital Diabetes Meeting 2020.Journal of diabetes science and technology · 2020
    Article
  19. Challenges and Strategies for Inpatient Diabetes Management in Older Adults.Diabetes spectrum : a publication of the American Diabetes Association · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elias K SpanakisDivision of Endocrinology, Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Guillermo E UmpierrezDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, Georgia.
Tariq SiddiquiDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland.
Min ZhanDepartment of Epidemiology and Public Health, University of Maryland, Baltimore, Maryland.
Soren SnitkerDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland.
Jeffrey C FinkDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
John D SorkinBaltimore Veterans Affairs Medical Center Geriatric Research, Education, and Clinical Center, Baltimore, Maryland.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Continuous Glucose Monitoring in Insulin Treated Hospitalized Veterans with DM2 at Higher Risk for HypoglycemiaI01CX001825 · VA · BALTIMORE VA MEDICAL CENTER · PI SPANAKIS, ILIAS · 2018 to 2023
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CSRD VA I01 CX001825NCATS NIH HHS UL1 TR002378NIA NIH HHS P30 AG028747NIDDK NIH HHS P30 DK072488NIDDK NIH HHS P30 DK111024
6 · The paper itself

Abstract

contextLow blood glucose concentrations during the discharge day may affect 30-day readmission and posthospital discharge mortality rates.

objectiveTo investigate whether patients with diabetes and low glucose values during the last day of hospitalization are at increased risk of readmission or mortality. DESIGN AND OUTCOMES: Minimum point of care glucose values were collected during the last 24 hours of hospitalization. We used adjusted rates of 30-day readmission rate, 30-, 90-, and 180-day mortality rates, and combined 30-day readmission/mortality rate to identify minimum glucose thresholds above which patients can be safely discharged. PATIENTS AND

settingNationwide cohort study including 843,978 admissions of patients with diabetes at the Veteran Affairs hospitals 14 years.

resultsThe rate ratios (RRs) increased progressively for all five outcomes as the minimum glucose concentrations progressively decreased below the 90 to 99 mg/dL category, compared with the 100 to 109 mg/dL category: 30-day readmission RR, 1.01 to 1.45; 30-day readmission/mortality RR, 1.01 to 1.71; 30-day mortality RR, 0.99 to 5.82; 90-day mortality RR, 1.01 to 2.40; 180-day mortality RR, 1.03 to 1.91. Patients with diabetes experienced greater 30-day readmission rates, 30-, 90- and 180-day postdischarge mortality rates, and higher combined 30-day readmission/mortality rates, with glucose levels <92.9 mg/dL, <45.2 mg/dL, 65.8 mg/dL, 67.3 mg/dL, and <87.2 mg/dL, respectively.

conclusionPatients with diabetes who had hypoglycemia or near-normal glucose values during the last day of hospitalization had higher rates of 30-day readmission and postdischarge mortality.

Indexed as

AgedBiomarkersBlood GlucoseCohort StudiesDiabetes MellitusFemaleFollow-Up StudiesHospitalizationHumansMaleMortalityPatient DischargePatient ReadmissionPrognosisSurvival RateTime FactorsBiomarkersBlood Glucose

Identifiers

PMID31042288
PMCPMC6642668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.