Evidence map›Paper›PMID 31042073›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2019

Physiological comparison of hemorrhagic shock and

Victor A Convertino, Kristen R Lye, Natalie J Koons, Michael J Joyner

Open access · bronzeAbstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Victor A Convertino1 Battlefield Health & Trauma Center for Human Integrative Physiology, U. S. Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
Kristen R Lye1 Battlefield Health & Trauma Center for Human Integrative Physiology, U. S. Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
Natalie J Koons1 Battlefield Health & Trauma Center for Human Integrative Physiology, U. S. Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
Michael J Joyner2 Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA.
United States Army Institute of Surgical Research · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impact statementDisturbance of normal homeostasis occurs when oxygen delivery and energy stores to the body's tissues fail to meet the energy requirement of cells. The work submitted in this review is important because it advances the understanding of inadequate oxygen delivery as it relates to early diagnosis and treatment of circulatory shock and its relationship to disturbance of normal functioning of cellular metabolism in life-threatening conditions of hemorrhage. We explored data from the clinical and exercise literature to construct for the first time a conceptual framework for defining the limitation of inadequate delivery of oxygen by comparing the physiology of hemorrhagic shock caused by severe blood loss to maximal oxygen uptake induced by intense physical exercise. We also provide a translational framework in which understanding the fundamental relationship between the body's reserve to compensate for conditions of inadequate oxygen delivery as a limiting factor to

Indexed as

Cell HypoxiaOxygen ConsumptionAcid-Base EquilibriumAdaptation, PhysiologicalAerobiosisAnimalsAutonomic Nervous SystemCardiac OutputEnergy MetabolismExsanguinationGlycolysisHemoglobinsHomeostasisHumansHypovolemiaLactatesHemoglobinsLactatesMyoglobinOxygenblood lactateblood pHcompensatory reserveOxygen deficitoxygen extraction reserve

Identifiers

PMID31042073
PMCPMC6552402
OpenAlexW2943731514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.