ReviewMedicina oral, patologia oral y cirugia bucal2019
Influence of microbiology on endodontic failure. Literature review.
Review in Medicina oral, patologia oral y cirugia bucal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07766707 (Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.), which is not on this map. Cited by 98 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Who cites it
98 citing papers in PubMed, 6 syntheses or guidelines pooled it, 255 citations in OpenAlex.
- Antimicrobial Efficacy of Nd:YAG Laser in Polymicrobial Root Canal Infections: A Systematic Review of In Vitro Studies.International journal of molecular sciences · 2025Pooled it
- Antibiofilm efficacy of plant extracts as root canal irrigants in endodontics: a systematic literature review.Frontiers in dental medicine · 2024Pooled it
- Prevalence of species of yellow, purple and green microbial complexes in endo-perio lesions: a systematic review.Brazilian oral research · 2024Pooled it
- Prevalence of postoperative pain after endodontic treatment using low and high concentrations of sodium hypochlorite: a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- Antimicrobial effectiveness of ultrasonic irrigation in root canal treatment: a systematic review of randomized clinical trials and meta-analysis.Clinical oral investigations · 2023Pooled it
- Comparison of Endodontic Failures between Nonsurgical Retreatment and Endodontic Surgery: Systematic Review and Meta-Analysis with Trial Sequential Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- `Effect of adjunctive antimicrobial photodynamic therapy on periapical healing and IL-6 modulation in apical periodontitis: a pilot randomized controlled study.Lasers in medical science · 2026Trial
- Impact XP-endo finisher on the 1-year follow-up success of posterior root canal treatments: a randomized clinical trial.Clinical oral investigations · 2023Trial
- Comparison of the Efficacy of Dexamethasone and Methylprednisolone in Infiltration Injection for Postendodontic Pain in Patients with Necrotic Pulp: A Randomized Controlled Clinical Trial.Pain research & management · 2022Trial
- Accessory Apical Foramina in Mandibular Second Molars with Mesial and Distal Root Canal Systems: An Ex Vivo Micro-CT Morphometric Study.Journal of clinical medicine · 2026Article
- Bibliometric Analysis of Plant-Derived Irrigants, Intracanal Medicaments, and Natural Compounds Against Enterococcus faecalis in Endodontics.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Photoinduced Fluorescence Changes in Selected Bacterial Strains Under 405 nm Laser Excitation: An In Vitro Hue-Based Monitoring Approach.Micromachines · 2026Article
- A Novel Laboratorial Approach to Evaluate Bacterial Microleakage of Endodontic Sealers.Current protocols · 2026Article
- [Selection of indications for apical microsurgery in different types of affected teeth].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Review
- Exploratory Evaluation of a Sodium Iodide-Based Root Canal Filling Formulation in a Canine Model ofPharmaceutics · 2026Article
- Antimicrobial efficacy of chitosan nanoparticles as intracanal medicament againstJournal of conservative dentistry and endodontics · 2026Article
- Article
- Bacterial contamination and diversity of dental unit waterlines across dental specialties, outlets and distinct times: heterotrophic bacteria counting and sequencing analysis.Journal of oral microbiology · 2026Article
- Regenerative Endodontic Procedure (REP) of a Previously Treated, Infected, Immature Permanent Incisor.Case reports in dentistry · 2026Article
- Oral Hygiene Habits and Toothbrush Contamination withInfection and drug resistance · 2026Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe main cause of endodontic failure is the persistence of microorganisms that cause an intraradicular or extratradicular infection and that become resistant to disinfection measures. The objective of this review is to identify the microbiota associated with endodontic failure, as well as the reasons why these microorganisms are capable of surviving basic disinfection measures. MATERIAL AND
methodsSystematic search of scientific articles in the databases PubMed with the following keywords "Endodontic Infections", "Endodontic Microbiology", "Endodontic Failure", "Enterococcus Faecalis", "Endodontics Retreatment" was carried out. Case reports and articles with publication date prior to 2000 were not included in this review.
resultsMost authors highlight E. faecalis as the main microorganism associated with endodontic failure, nevertheless there are recent studies that isolate, to a greater extent, other bacteria such as Fusobacterium nucleatum and Propionibacterium. DISCUSSION: These microorganisms have in common the following proprieties, which make them able to escape the disinfection measures: the ability to form a biofilm, to locate in areas unreachable to root canal instrumentation techniques, synergism, the ability to express survival genes and activate alternative metabolic pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.