Evidence map›Paper›PMID 31041697›Full record

ArticleInternational journal of computer assisted radiology and surgery2019

Liver tissue segmentation in multiphase CT scans using cascaded convolutional neural networks.

Farid Ouhmich, Vincent Agnus, Vincent Noblet, Fabrice Heitz, Patrick Pessaux

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Article in International journal of computer assisted radiology and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Harnessing the Power of AI for Enhanced Diagnosis and Treatment of Hepatocellular Carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
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  16. Radiomics in hepatocellular carcinoma: A state-of-the-art review.World journal of gastrointestinal oncology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Farid OuhmichNouvel Hôpital Civil, Institut Hospitalo-Universitaire de Strasbourg, 1 place de l'Hôpital, 67000, Strasbourg, France. farid.ouhmich@ihu-strasbourg.eu.
Vincent AgnusNouvel Hôpital Civil, Institut Hospitalo-Universitaire de Strasbourg, 1 place de l'Hôpital, 67000, Strasbourg, France.ORCID http://orcid.org/0000-0001-9554-6492
Vincent NobletICube UMR 7357, University of Strasbourg, CNRS, FMTS, 300 bd Sébastien Brant, 67412, Illkirch, France.
Fabrice HeitzICube UMR 7357, University of Strasbourg, CNRS, FMTS, 300 bd Sébastien Brant, 67412, Illkirch, France.
Patrick PessauxDepartment of Hepato-Biliary and Pancreatic Surgery, Nouvel Hôpital Civil, Institut Hospitalo-Universitaire de Strasbourg, 1 place de l'Hôpital, 67000, Strasbourg, France.

Funding

10-IAHU-0002 10-IAHU-0002
6 · The paper itself

Abstract

purposeWe address the automatic segmentation of healthy and cancerous liver tissues (parenchyma, active and necrotic parts of hepatocellular carcinoma (HCC) tumor) on multiphase CT images using a deep learning approach.

methodsWe devise a cascaded convolutional neural network based on the U-Net architecture. Two strategies for dealing with multiphase information are compared: Single-phase images are concatenated in a multi-dimensional features map on the input layer, or output maps are computed independently for each phase before being merged to produce the final segmentation. Each network of the cascade is specialized in the segmentation of a specific tissue. The performances of these networks taken separately and of the cascaded architecture are assessed on both single-phase and on multiphase images.

resultsIn terms of Dice coefficients, the proposed method is on par with a state-of-the-art method designed for automatic MR image segmentation and outperforms previously used technique for interactive CT image segmentation. We validate the hypothesis that several cascaded specialized networks have a higher prediction accuracy than a single network addressing all tasks simultaneously. Although the portal venous phase alone seems to provide sufficient contrast for discriminating tumors from healthy parenchyma, the multiphase information brings significant improvement for the segmentation of cancerous tissues (active versus necrotic part).

conclusionThe proposed cascaded multiphase architecture showed promising performances for the automatic segmentation of liver tissues, allowing to reliably estimate the necrosis rate, a valuable imaging biomarker of the clinical outcome.

Indexed as

Deep LearningNeural Networks, ComputerAlgorithmsBiomarkersCarcinoma, HepatocellularHumansImage Processing, Computer-AssistedLiverLiver NeoplasmsNecrosisPattern Recognition, AutomatedReproducibility of ResultsTomography, X-Ray ComputedBiomarkersFully convolutional networks (FCNs)Hepatocellular carcinomaLiver tissuesMultiphase CTSemantic segmentation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.