Evidence map›Paper›PMID 31041576›Full record

ArticleClinical oral investigations2020

Apical periodontitis as potential source of infection in patients with lymphoma treated with chemotherapy.

Kristina Skallsjö, Jan-Erik Johansson, Peter Jonasson, Bengt Hasséus

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Prevalence of Apical Periodontitis in patients with Multiple Myeloma.Medicina oral, patologia oral y cirugia bucal · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kristina SkallsjöClinic of Orofacial Medicine, Mölndal, Public Dental Service, 431 80, Mölndal, Sweden.
Jan-Erik JohanssonDepartment of Hematology and Coagulation, Sahlgrenska University Hospital, Gothenburg, Sweden.
Peter JonassonDepartment of Endodontology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Box 450, 405 30, Gothenburg, Sweden.
Bengt HasséusDepartment of Oral Medicine and Pathology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Box 450, 405 30, Gothenburg, Sweden. Bengt.Hasseus@odontologi.gu.se.
University of Gothenburg · SEPublic Dental Service Västra Götaland · SE

Funding

Local Research and Development Board for Gothenburg and Södra Bohuslän, Region Västra Götaland, Sweden. VGFOUGSB-394111, VGFOUGSB-394241.
6 · The paper itself

Abstract

objectivesTo investigate signs of infection and infection-related complications of apical periodontitis (AP) in patients who underwent chemotherapy for lymphoma. MATERIALS AND

methodsData were collected retrospectively from the dental and medical records of patients receiving chemotherapy for lymphoma. Based on the findings from a dental evaluation made in conjunction with chemotherapy, the patients were divided into two groups, patients with or without teeth with AP.

resultsEighty-six of the 213 patients had one or more teeth with AP and received no planned dental treatment for this condition, while 127 patients had no AP-affected teeth. During chemotherapy, seven patients (8%) developed local symptoms related to teeth with AP, while no patients in the control group developed symptoms of AP. No significant differences were found with respect to the administration of antibiotics related to dental infection or hospital admission events due to fever or infection, between the group with AP and the group without AP.

conclusionsAP is a common finding and exacerbation seems more common in patients diagnosed with chronic AP than in patients without chronic AP. The presence of chronic AP in patients treated with chemotherapy for lymphoma is not linked to additional medical complications that require hospital admission owing to fever/infection. CLINICAL RELEVANCE: Knowledge regarding infection-related complications of AP in patients with lymphoma treated with chemotherapy will guide clinical decision-making by identifying those patients who warrant treatment. This will allow dental interventions to be postponed until completion of chemotherapy, without serious medical complications. The results of this study serve as a basis for larger prospective studies.

Indexed as

Periapical PeriodontitisAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsBleomycinDacarbazineDoxorubicinFemaleHodgkin DiseaseHumansInfectionsLymphomaMaleProspective StudiesRetrospective StudiesRoot Canal TherapyVinblastineAntineoplastic AgentsBleomycinDacarbazineDoxorubicinVinblastineApical periodontitisExacerbationImmunosuppressionLymphomaOral infection

Identifiers

PMID31041576
OpenAlexW2942590598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.