Evidence map›Paper›PMID 31041537›Full record

ArticleJournal of materials science. Materials in medicine2019

In vitro cytotoxicity of calcium phosphate cement reinforced with multiwalled carbon nanotubes.

Lubomir Medvecky, Maria Giretova, Ruzena Kralikova, Simona Medvecka, Jaroslav Briancin

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lubomir MedveckyInstitute of Materials Research of SAS, Watsonova 47, Kosice, 040 01, Slovakia. lmedvecky@saske.sk.ORCID http://orcid.org/0000-0002-1720-2034
Maria GiretovaInstitute of Materials Research of SAS, Watsonova 47, Kosice, 040 01, Slovakia.
Ruzena KralikovaDepartment of Process and Environmetal Engineering, Faculty of Mechanical Engineering, Technical University of Kosice, Letna 9, Kosice, 040 01, Slovakia.
Simona MedveckaDepartment of Process and Environmetal Engineering, Faculty of Mechanical Engineering, Technical University of Kosice, Letna 9, Kosice, 040 01, Slovakia.
Jaroslav BriancinInstitute of Geotechnics of SAS, Watsonova 43, Kosice, 040 01, Slovakia.

Funding

the Slovak Grant Agency of the Ministry of Education of the Slovak Republic and the Slovak Academy of Sciences 2/0047/17
6 · The paper itself

Abstract

The in vitro cytotoxicity of both the multiwalled carbon nanotubes (MWCNT) in suspension with culture medium and the tetracalcium phosphate/monetite cement with addition of 0.8 wt% of MWCNTs on fibroblasts and osteoblasts were studied. The cytotoxicity was evaluated by MTS test (formazan) and live/dead staining. No cytotoxicity of MWCNT extract was measured contrary to about 60% reduction in proliferation of fibroblasts in MWCNT suspension as compared with negative control. The several contact cytotoxicity of MWCNT composite cement surfaces on seeded cells was demonstrated by MTS test and live/dead staining of damaged fibroblasts and dead osteoblasts after 72 h of culture. The detailed microstructure analysis showed a significant refinement of the surface texture due to the formation of thin needle-like hydroxyapatite particles on MWCNTs and this effect could be responsible for cytotoxicity of composites.

Indexed as

AnimalsBiocompatible MaterialsBone CementsCalcium PhosphatesCell LineCell SurvivalMaterials TestingMiceNanotubes, CarbonBiocompatible MaterialsBone CementsCalcium PhosphatesNanotubes, Carbontetracalcium phosphate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.