ArticleOpen forum infectious diseases2019
Clinical Yield of a Molecular Diagnostic Panel for Enteric Pathogens in Adult Outpatients With Diarrhea and Validation of Guidelines-Based Criteria for Testing.
Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Impact of the BioFireBMC infectious diseases · 2026Article
- Repeat multiplex PCR gastrointestinal panel testing within 14 days yields minimal additional diagnostic information: a multicenter cohort study.Infection control and hospital epidemiology · 2026Article
- Multiplex Polymerase Chain Reaction Panels for Gastrointestinal Infections: Current Evidence, Regulatory Hurdles, and the Way Forward.Open forum infectious diseases · 2025Article
- Syndromic Gastrointestinal Panel Diagnostic Tests Have Changed our Understanding of the Epidemiology ofOpen forum infectious diseases · 2024Article
- Evaluating outpatient diagnostic stewardship of comprehensive polymerase chain reactionAntimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Travel-related gastrointestinal diseases: Assessment and management.Public health challenges · 2022Review
- Changing Diagnostic Testing Practices for Foodborne Pathogens, Foodborne Diseases Active Surveillance Network, 2012-2019.Open forum infectious diseases · 2022Article
- Performance Evaluation of the Novodiag Bacterial GE+ Multiplex PCR Assay.Journal of clinical microbiology · 2020Article
- Stewardship of Molecular Diagnostics in Transplant Viral Infections.Transplant infectious disease : an official journal of the Transplantation SocietyReview
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundMolecular diagnostic panels for enteric pathogens offer increased sensitivity and reduced turnaround time. However, many pathogen detections do not change clinical management, and the cost is substantial.
methodsWe performed a retrospective chart review of adult outpatients with diarrhea at the University of Virginia who had samples tested by the FilmArray Gastrointestinal Panel (BioFire Diagnostics, Salt Lake City, UT) to identify the clinical yield and to validate the clinical criteria for testing recommended in the 2017 Infectious Diseases Society of America (IDSA) guidelines.
resultsWe analyzed 629 tests sent from adult outpatients with diarrhea between March 23, 2015, and July 18, 2016. A pathogen was detected in 127 of 629 specimens (20.2%). The most common pathogens were enteropathogenic
conclusionsThe clinical yield of molecular diagnostic testing in this population was low. Compliance with IDSA guidelines in adult outpatients with diarrhea could reduce testing by approximately one-third.
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