Evidence map›Paper›PMID 31041312›Full record

ReviewFrontiers in cell and developmental biology2019

Immunogenic Cell Death and Immunotherapy of Multiple Myeloma.

Alfonso Serrano-Del Valle, Alberto Anel, Javier Naval, Isabel Marzo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 193 citations in OpenAlex.

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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alfonso Serrano-Del ValleDepartment of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza, Spain.
Alberto AnelDepartment of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza, Spain.
Javier NavalDepartment of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza, Spain.
Isabel MarzoDepartment of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza, Spain.
Universidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decades, immunotherapy has demonstrated a prominent clinical efficacy in a wide variety of human tumors. For many years, apoptosis has been considered a non-immunogenic or tolerogenic process whereas necrosis or necroptosis has long been acknowledged to play a key role in inflammation and immune-related processes. However, the new concept of "immunogenic cell death" (ICD) has challenged this traditional view and has granted apoptosis with immunogenic abilities. This paradigm shift offers clear implications in designing novel anti-cancer therapeutic approaches. To date, several screening studies have been carried out to discover

Indexed as

danger-associated molecular patternER stressimmunogenic cell deathimmunotherapymultiple myeloma

Identifiers

PMID31041312
PMCPMC6476910
OpenAlexW2938158852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.