Evidence map›Paper›PMID 31041260›Full record

ArticleJournal of family medicine and primary care2019

Tracking lipid profile and atherogenic indices in the prediabetics of Andaman Nicobar Islands: A retrospective hospital-based study.

Montosh Chakraborty, Shivakrishna Gouroju, Prerna Singh, Pandurang V Thatkar, Debajit Bagchi

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Montosh ChakrabortyDepartment of Biochemistry, AIIMS, Mangalagiri, Guntur, Andhra Pradesh, India.
Shivakrishna GourojuDepartment of Biochemistry, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, India.
Prerna SinghDepartment of Biochemistry, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, India.
Pandurang V ThatkarDepartment of Community Medicine, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, India.
Debajit BagchiDepartment of Biochemistry, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, India.
ICAR - Central Island Agricultural Research Institute · INInstitute of Medical Sciences · INAll India Institute of Medical Sciences Bhopal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextCardio vascular disease (CVD) is the leading cause of mortality and morbidity in diabetes mellitus (DM) contributing to 65% of all deaths with diabetic complications. The most important cause of CVD is atherosclerosis, and dyslipidemia acts as a marker of developing atherosclerosis. The derangement of lipid profile and atherogenic indices start in the prediabetic state, much before the development of DM. Detection of the deranged lipid profile and atherogenic indices in the prediabetic state can help devise the aggressive treatment strategy right from this stage, so as to arrest the development of CVD as a complication of diabetes.

aimsTo compare the lipid profile and atherogenic indices of prediabetics with controls and diabetics. SETTINGS AND

designThe electronic medical records of 239 subjects were reviewed retrospectively. MATERIALS AND

methodsAbout 187 cases consisting of 137 diabetics and 50 prediabetics were evaluated for serum fasting blood sugar, post prandial blood sugar, HbA1c, total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDLc), and low-density lipoprotein cholesterol (LDLc). Atherogenic indices [TC/HDLc, LDLc/HDLc, (TC-HDLc)/HDLc, TG/HDLc] were also evaluated in the two groups. Rest 52 age- and sex-matched subjects were taken as controls. STATISTICAL ANALYSIS USED: The comparisons were evaluated using SPSS statistical package version 20.

resultsTC, TG, LDLc, and the atherogenic indices were significantly increased in prediabetics as compared with controls. HDLc was significantly decreased in prediabetics.

conclusionsThe altered lipid profile and atherogenic indices in prediabetics signify the increased susceptibility of prediabetics to CVD in the long run. Hence, we recommend screening of prediabetics for dyslipidemia to arrest the development of cardiovascular complications.

Indexed as

Atherogenic indicescardiovascular diseasesdiabeticslipid profileprediabetics

Identifiers

PMID31041260
PMCPMC6482723
OpenAlexW2925989929

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.