Evidence map›Paper›PMID 31040926›Full record

ArticleOncotarget2019

Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression.

Badal Chandra Roy, Ishfaq Ahmed, Satish Ramalingam, Venkatakrishna Jala, Bodduluri Haribabu, Prabhu Ramamoorthy, John Ashcraft, Joseph Valentino, Shrikant Anant, Venkatesh Sampath and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Badal Chandra Roy *Departments of Surgery and Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Ishfaq Ahmed *Departments of Surgery and Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Satish RamalingamDepartment of Genetic Engineering, School of Bio-Engineering, SRM Institute of Science and Technology, Kattankulathur, Kanchipuram, Tamil Nadu, India.
Venkatakrishna JalaJames Graham Brown Cancer Center and Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Bodduluri HaribabuJames Graham Brown Cancer Center and Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Prabhu RamamoorthyDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
John AshcraftDepartments of Surgery and Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Joseph ValentinoDepartments of Surgery and Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Shrikant AnantDepartments of Surgery and Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Venkatesh SampathDivision of Neonatology, Children's Mercy Hospital, Kansas City, MO, USA.
Shahid UmarDepartments of Surgery and Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
University of Kansas Medical Center · USUniversity of Louisville · USChildren's Mercy Hospital · USSRM Institute of Science and Technology · INThe University of Kansas Cancer Center · US

Funding

Bitter Melon Component and Colon Cancer PreventionR01CA190291 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ANANT, SHRIKANT, UMAR, SHAHID · 2014 to 2018
$2.7M
Single Immunoglobulin Interleukin-1 Related Receptor and necrotizing enterocolitis in premature infantsR01DK117296 · NIDDK · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI SAMPATH, VENKATESH, UMAR, SHAHID · 2018 to 2022
$2.6M
Epigenetics and Infection-induced EMT of Colonic Crypts - Target for ChemopreventionR01CA185322 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI UMAR, SHAHID · 2015 to 2019
$1.9M
NCI NIH HHS R01 CA185322NCI NIH HHS R01 CA190291NIDDK NIH HHS R01 DK117296
6 · The paper itself

Abstract

Autophagy may play a critical role in colon cancer stem cells (CCSCs)-related cancer development. Here, we investigate whether accumulation of infection/injury-induced CCSCs due to impaired autophagy influences colon cancer development and progression. When

Indexed as

autophagycolon cancerdclk1metastasisstem cells

Identifiers

PMID31040926
PMCPMC6481322
OpenAlexW2944154866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.