ArticleFrontiers in physiology2019
Exercise Overrides Blunted Hypoxic Ventilatory Response in Prematurely Born Men.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Physiological responses to exercise in survivors of preterm birth: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Nocturnal pulse oxygen saturation dynamics at simulated high altitude: Predictive value for acute mountain sickness in healthy men born pre-term.Experimental physiology · 2025Article
- Antioxidant and neurodevelopmental gene polymorphisms in prematurely born individuals influence hypoxia-related oxidative stress.Scientific reports · 2024Article
- Increasing airway obstruction through life following bronchopulmonary dysplasia: a meta-analysis.ERJ open research · 2023Review
- Respiratory responses to hypoxia during rest and exercise in individuals born pre-term: a state-of-the-art review.European journal of applied physiology · 2022Review
- Urine and FecalMetabolites · 2022Article
- Physiological aspects of cardiopulmonary dysanapsis on exercise in adults born preterm.The Journal of physiology · 2022Review
- Effects of Pre-Term Birth on the Cardio-Respiratory Responses to Hypoxic Exercise in Children.Life (Basel, Switzerland) · 2022Article
- The ventilatory response to hypoxia is blunted in some preterm infants during the second year of life.Frontiers in pediatrics · 2022Article
- Preterm birth: Potential risk factor for greater COVID-19 severity?Respiratory physiology & neurobiology · 2020Article
- Cardio-respiratory, oxidative stress and acute mountain sickness responses to normobaric and hypobaric hypoxia in prematurely born adults.European journal of applied physiology · 2020Article
- Effect of pre-term birth on oxidative stress responses to normoxic and hypoxic exercise.Redox biology · 2020Article
- Relationship between cardiorespiratory phase coherence during hypoxia and genetic polymorphism in humans.The Journal of physiology · 2020Article
- Variation of Cognitive Function During a Short Stay at Hypobaric Hypoxia Chamber (Altitude: 3842 M).Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePre-term birth provokes life-long anatomical and functional respiratory system sequelae. Although blunted hypoxic ventilatory response (HVR) is consistently observed in pre-term infants, it remains unclear if it persists with aging and, moreover, if it influences hypoxic exercise capacity. In addition, it remains unresolved whether the previously observed prematurity-related alterations in redox balance could contribute to HVR modulation.
methodsTwenty-one prematurely born adult males (gestational age = 29
resultsResting HVR was lower in the pre-term (0.21
conclusionThese findings indicate that blunted resting HVR in prematurely born men persists into adulthood. Also, active adults born prematurely seem to tolerate hypoxic exercise well and should, hence, not be discouraged to engage in physical activities in hypoxic environments. Nevertheless, the blunted resting HVR and greater desaturation observed in the pre-term born individuals warrant caution especially during prolonged hypoxic exposures.
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Registered trials
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