ArticleNeuropsychiatric disease and treatment2019
Cognitive function, depression, and anxiety in patients undergoing radical prostatectomy with and without adjuvant treatment.
Article in Neuropsychiatric disease and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Evaluation of Event-Related Potentials in Somatic Diseases - Systematic Review.Applied psychophysiology and biofeedback · 2024Pooled it
- A systematic review of risk factors associated with depression and anxiety in cancer patients.PloS one · 2024Pooled it
- Trial
- Cognitive function in patients undergoing robotic radical prostatectomy - 1 year follow up.Journal of robotic surgery · 2026Article
- Smoking Habits, Physical Activity and BMI as Predictors of Cognitive and Affective Function in Patients with Prostate Cancer.Research and reports in urology · 2026Article
- Are pNF-H, IL-6, BDNF, and NSP Reliable Biomarkers of Cognitive Function in Prostate Cancer Patients?International journal of molecular sciences · 2025Article
- Impact of Androgen Deprivation Therapy on Cognitive Function of Elderly Men With Prostate Cancer.Cureus · 2024Article
- Exploring the Hidden Struggles: A Qualitative Insight into Urinary Incontinence Among Prostate Cancer Survivors Post-Surgery.Patient preference and adherence · 2024Article
- Gender-modulated influence of BDNF concentration and Val66Met polymorphism on cognitive outcomes in chronic limb ischemia patients.Frontiers in endocrinology · 2024Article
- Living with prostate cancer: a mixed-method evaluation of group therapy intervention to alleviate psychological distress in a Canadian setting.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Application and Mechanisms of Internet-Based Cognitive Behavioral Therapy (iCBT) in Improving Psychological State in Cancer Patients.Journal of Cancer · 2023Review
- [Testosterone and Alzheimer's disease].Problemy endokrinologii · 2022Article
- Impact of Testosterone on Alzheimer's Disease.The world journal of men's health · 2022Review
- Self-perceived cognitive functioning and quality of life among cancer survivors: results from the PROFILES registry.Journal of cancer survivorship : research and practice · 2022Article
- Quality of Life of Prostate Cancer Patients Undergoing Prostatectomy and Affective Temperament.Cancer management and research · 2022Article
- Undergoing radical treatment for prostate cancer and its impact on wellbeing: A qualitative study exploring men's experiences.PloS one · 2022Article
- Prostate-Specific Antigen and Testosterone Levels as Biochemical Indicators of Cognitive Function in Prostate Cancer Survivors and the Role of Diabetes.Journal of clinical medicine · 2021Article
- Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?World journal of urology · 2021Article
- Cognitive and Psychological Impacts of Different Treatment Options for Prostate Cancer: A Critical Analysis.Current urology · 2020Review
- An Updated Review: Androgens and Cognitive Impairment in Older Men.Frontiers in endocrinology · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProstate cancer (PC) is one of the most common malignant tumors in developed countries. Both PC and treatment for PC have an adverse impact on physical and mental well-being, and are associated with decreased quality of life. The aim of the present study was to examine the relationship between neuropsychological symptoms and clinical course in PC patients undergoing radical prostatectomy with or without adjunct therapy.
methodsThe cohort comprised 100 patients aged 50-77 years who underwent radical, laparoscopic prostatectomy for PC. Twenty-three patients with a more advanced clinical stage also received adjuvant therapy (radiotherapy and hormonotherapy). Clinical evaluation included self-report assessment, physical examination, and biochemical tests (testosterone and prostate-specific antigen). In addition, the presence and intensity of sexual dysfunction, urinary dysfunction, anxiety-depressive symptoms, and cognitive dysfunction were assessed.
resultsThe group of patients undergoing complex therapy was characterized by a significantly worse result of deferred memory (
conclusionPatients undergoing both surgical and adjunct therapy for PC are at risk for psychological burden and cognitive disorders. In the present cohort, physical complications of therapy were associated with depression, anxiety, and delayed memory dysfunction. Furthermore, this study has proven that fewer complications after surgery are associated with better psychological and cognitive functioning. Appropriate neuropsychological and psychiatric care can improve compliance and quality of life among patients after prostatectomy.
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