Evidence map›Paper›PMID 31040668›Full record

ArticleInternational journal of nanomedicine2019

A smartphone-assisted pressure-measuring-based diagnosis system for acute myocardial infarction diagnosis.

Guolin Hong, Gang Rui, Dongdong Zhang, Mingjian Lian, Yuanyuan Yang, Ping Chen, Huijing Yang, Zhichao Guan, Wei Chen, Yan Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Guolin HongDepartment of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361005, People's Republic of China.
Gang RuiDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Xiamen University, Xiamen 361005, People's Republic of China.
Dongdong ZhangDepartment of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361005, People's Republic of China.
Mingjian LianDepartment of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361005, People's Republic of China.
Yuanyuan YangDepartment of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361005, People's Republic of China.
Ping ChenDepartment of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361005, People's Republic of China.
Huijing YangDepartment of Clinical Medicine, Fujian Medical University, Fuzhou 350108, People's Republic of China.
Zhichao GuanDepartment of Research and development, Xiamen Passtech Co.,Ltd., Xiamen 361101, People's Republic of China.
Wei ChenHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Department of Pharmaceutical Analysis, Fujian Medical University, Fuzhou 350004, People's Republic of China, chenandhu@163.com.
Yan WangDepartment of Cardiology, the Affiliated Cardiovascular Hospital of Xiamen University, Medical College of Xiamen University, Xiamen 361004, People's Republic of China, wyxiamen@126.com.
First Affiliated Hospital of Xiamen University · CNFujian Medical University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute myocardial infarction (AMI), usually caused by atherosclerosis of coronary artery, is the most severe manifestation of coronary artery disease which results in a large amount of death annually. A new diagnosis approach with high accuracy, reliability and low measuring-time-consuming is essential for AMI quick diagnosis. PURPOSE: The objective of this study was to develop a new point-of-care testing system with high accuracy and reliability for AMI quick diagnosis. PATIENTS AND

methods50 plasma samples of acute myocardial infarction patients were analyzed by developed Smartphone-Assisted Pressure-Measuring-Based Diagnosis System (SPDS). The concentration of substrate was firstly optimized. The effect of antibody labeling and matrix solution on measuring result were then evaluated. And standard curves for cTnI, CK-MB and Myo were built for clinical sample analysis. The measuring results of 50 clinical samples were finally evaluated by comparing with the measuring result obtained by CLIA.

resultsThe concentration of substrate H

conclusionDue to its small device size, high sensitivity and accuracy, SPDS showed a bright potential for point-of-care testing (POCT) applications.

Indexed as

Blood PressureSmartphoneAntibodiesBiomarkersCatalysisFemaleHumansHydrogen PeroxideMaleMiddle AgedMyocardial InfarctionNanoparticlesPlatinumReference StandardsReproducibility of ResultsSensitivity and SpecificityAntibodiesBiomarkersHydrogen PeroxidePlatinumacute myocardial infarctiondiagnosispressure sensorPt nanoparticlesmartphone

Identifiers

PMID31040668
PMCPMC6459154
OpenAlexW2933417952

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.