ReviewMissouri medicine
The Cardiovascular Effects of Marijuana: Are the Potential Adverse Effects Worth the High?
Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 103 citations in OpenAlex.
- The Characteristics and Circumstances of Fatal Interpersonal Strangulation in Australian Adults.Journal of interpersonal violence · 2026Article
- Article
- Lifetime Cannabis, Non-Cigarette Tobacco, and Illicit Drug Use and Cardiovascular Disease Among Young and Middle-Aged U.S. Adults.American journal of lifestyle medicine · 2025Article
- Rare but relevant: Cannabis use and myocardial infarction.Addiction (Abingdon, England) · 2025Review
- Article
- Parasympathetic decreases immediately following self-reported cannabis smoking among adults living with cannabis use disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025Article
- Recurrent Peripheral Artery Disease in a 45-Year-Old Male Without Hypercoagulable Comorbidities.Cureus · 2025Article
- Comparison between pediatric and adult acute natural cannabinoids toxicity: A 5-year retrospective study with special consideration of acute synthetic cannabinoids toxicity.Toxicology reports · 2025Article
- Ocular effects of synthetic cannabinoids: a case-control study.Eye (London, England) · 2025Observational
- Acute cannabis intoxication among the paediatric population.Frontiers in toxicology · 2025Review
- Review
- Regular cannabis smoking and carotid artery calcification in the Multi-Ethnic Study of Atherosclerosis (MESA).Vascular medicine (London, England) · 2024Article
- The Impact of Cannabidiol Treatment on Anxiety Disorders: A Systematic Review of Randomized Controlled Clinical Trials.Life (Basel, Switzerland) · 2024Review
- Role of Point-of-Care Gastric Ultrasound in Advancing Perioperative Fasting Guidelines.Diagnostics (Basel, Switzerland) · 2024Review
- Contemporary nationwide trends in major adverse cardiovascular events in young cannabis users without concomitant tobacco, alcohol, cocaine use.World journal of cardiology · 2024Article
- Cannabis Use Variations and Myocardial Infarction: A Systematic Review.Journal of clinical medicine · 2024Review
- Review
- Associations between Cannabis Consumption Methods and Cannabis Risk Perception.International journal of environmental research and public health · 2024Article
- Association of Cannabis Use Disorder with Major Adverse Cardiac and Cerebrovascular Events in Older Non-Tobacco Users: A Population-Based Analysis.Medical sciences (Basel, Switzerland) · 2024Article
- Perceptions, Attitudes, and Knowledge of Cannabis and its Use: A Qualitative Study among Herbal Heart Study Young Adult Cannabis Consumers in South Florida.Preventive medicine reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marijuana is the most commonly abused illicit drug in the United States (US) and much of the Westernized World with a steadily increasing prevalence in usage and abuse over the past decade, especially among adolescents. Much of the available data on 9-tetrahydrocannabinol (THC), the main psychoactive ingredient in marijuana, relates to its neurological effects and anti-emetic properties, with very little on the cardiovascular (CV) effects of THC. Available literature shows that THC has three major effects on the CV and the peripheral vasculature in the form of "cannabis arteritis," cannabis-induced vasospasms, and platelet aggregation, with an unknown verdict on the relationship between marijuana use and atherosclerosis progression. This manuscript reviews these effects and possible mechanisms of action. Moreover, limitations on current views of marijuana and indirect causes of CV toxicity will be investigated, such as concurrent drug use, lifestyle, and mental health. The effects of marijuana on the CV system are extremely worrisome and likely need more attention due to the growing legalization of cannabis for medicinal and recreational use across the US. As a result, awareness among health care professionals about potential side effects and toxicities associated with acute and chronic exposure of cannabis will increase in importance.
Indexed as
Identifiers
31040502PMC6461323W2980887588What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.