Evidence map›Paper›PMID 31040385›Full record

ArticleBritish journal of cancer2019

Understanding the impact of socioeconomic differences in colorectal cancer survival: potential gain in life-years.

Elisavet Syriopoulou, Eva Morris, Paul J Finan, Paul C Lambert, Mark J Rutherford

Abstract read
In one paragraph

Article in British journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elisavet SyriopoulouBiostatistics Research Group, Department of Health Sciences, University of Leicester, University Road, LE1 7RH, Leicester, UK. e.syriopoulou@leicester.ac.uk.ORCID http://orcid.org/0000-0002-5749-4094
Eva MorrisCancer Epidemiology Group, Institute of Medical Research at St James's and Institute of Data Analytics, University of Leeds, Worsley Building, Leeds, LS2 9JT, UK.
Paul J FinanCancer Epidemiology Group, Institute of Medical Research at St James's and Institute of Data Analytics, University of Leeds, Worsley Building, Leeds, LS2 9JT, UK.
Paul C LambertBiostatistics Research Group, Department of Health Sciences, University of Leicester, University Road, LE1 7RH, Leicester, UK.
Mark J RutherfordBiostatistics Research Group, Department of Health Sciences, University of Leicester, University Road, LE1 7RH, Leicester, UK.

Funding

Cancer Research UK 18262Department of Health DRF-2017-10-116Medical Research Council MR/L01629X/1
6 · The paper itself

Abstract

backgroundColorectal cancer prognosis varies substantially with socioeconomic status. We investigated differences in life expectancy between socioeconomic groups and estimated the potential gain in life-years if cancer-related survival differences could be eliminated.

methodsThis population-based study included 470,000 individuals diagnosed with colon and rectal cancers between 1998 and 2013 in England. Using flexible parametric survival models, we obtained a range of life expectancy measures by deprivation status. The number of life-years that could be gained if differences in cancer-related survival between the least and most deprived groups were removed was also estimated.

resultsWe observed up to 10% points differences in 5-year relative survival between the least and most deprived. If these differences had been eliminated for colon and rectal cancers diagnosed in 2013 then almost 8231 and 7295 life-years would have been gained respectively. This results for instance in more than 1-year gain for each colon cancer male patient in the most deprived group on average. Cancer-related differences are more profound earlier on, as conditioning on 1-year survival the main reason for socioeconomic differences were factors other than cancer.

conclusionThis study highlights the importance of policies to eliminate socioeconomic differences in cancer survival as in this way many life-years could be gained.

Indexed as

Life ExpectancySocial ClassAgedColorectal NeoplasmsFemaleHumansMale

Identifiers

PMID31040385
PMCPMC6738073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.