Evidence map›Paper›PMID 31040365›Full record

ArticleScientific reports2019

Annexin A7 is required for ESCRT III-mediated plasma membrane repair.

Stine Lauritzen Sønder, Theresa Louise Boye, Regine Tölle, Jörn Dengjel, Kenji Maeda, Marja Jäättelä, Adam Cohen Simonsen, Jyoti K Jaiswal, Jesper Nylandsted

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 106 citations in OpenAlex.

  1. Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repair.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Membrane interaction of cyanobacterial and chloroplast ESCRT-III proteins.The Plant journal : for cell and molecular biology · 2026
    Review
  8. ESCRT-III function in membrane fission and repair.Nature reviews. Molecular cell biology · 2026
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Pseudouridine selects RNAs for extracellular transport.bioRxiv : the preprint server for biology · 2025
    Article
  14. Review
  15. Article
  16. Revisiting the role of Annexins in membrane trafficking.Cellular and molecular life sciences : CMLS · 2025
    Review
  17. Review
  18. Article
  19. Article
  20. Keratinocyte-Derived Exosomes in Painful Diabetic Neuropathy.bioRxiv : the preprint server for biology · 2024
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Stine Lauritzen SønderUnit for Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.
Theresa Louise BoyeUnit for Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.
Regine TölleDepartment of Dermatology, Medical Center, University of Freiburg, 79104, Freiburg, Germany.
Jörn DengjelDepartment of Dermatology, Medical Center, University of Freiburg, 79104, Freiburg, Germany.ORCID http://orcid.org/0000-0002-9453-4614
Kenji MaedaUnit for Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.
Marja JäätteläUnit for Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5950-7111
Adam Cohen SimonsenDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.ORCID http://orcid.org/0000-0003-1937-8524
Jyoti K JaiswalChildren's National Health System, Center for Genetic Medicine Research, George Washington University School of Medicine and Health Sciences, 111 Michigan Avenue, NW, Washington, DC, 20010-2970, USA.ORCID http://orcid.org/0000-0002-5992-5185
Jesper NylandstedUnit for Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark. jnl@cancer.dk.ORCID http://orcid.org/0000-0001-6474-5093
Danish Cancer Society · DKUniversity of Copenhagen · DKUniversity of Fribourg · CHChildren's National · USUniversity of Southern Denmark · DK

Funding

Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2016 to 2020
$5.9M
Understanding the mechanism and role of cell membrane repair in Miyoshi MyopathyR01AR055686 · NIAMS · ROCKEFELLER UNIVERSITY · PI JAISWAL, JYOTI K · 2008 to 2021
$3.6M
NIAMS NIH HHS R01 AR055686NICHD NIH HHS U54 HD090257
6 · The paper itself

Abstract

The plasma membrane of eukaryotic cells forms the essential barrier to the extracellular environment, and thus plasma membrane disruptions pose a fatal threat to cells. Here, using invasive breast cancer cells we show that the Ca

Indexed as

Annexin A7Apoptosis Regulatory ProteinsCalcium-Binding ProteinsCell Cycle ProteinsCell MembraneDigitoninEndosomal Sorting Complexes Required for TransportFemaleHeLa CellsHumansMCF-7 CellsAnnexin A7Apoptosis Regulatory ProteinsCalcium-Binding ProteinsCell Cycle ProteinsDigitoninEndosomal Sorting Complexes Required for TransportPDCD6IP protein, humanPDCD6 protein, human

Identifiers

PMID31040365
PMCPMC6491720
OpenAlexW2943583417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.