ArticleScientific reports2019
Factors associated with chronic obstructive pulmonary disease exacerbation, based on big data analysis.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 56 citations in OpenAlex.
- Development of a daily predictive model for the exacerbation of chronic obstructive pulmonary disease.Scientific reports · 2023Trial
- COPD prescription patterns after the 2018 Japan floods: analysis of national data.Scientific reports · 2026Article
- Cardiovascular components of the COTE index predict acute exacerbations and healthcare costs in patients with chronic obstructive pulmonary disease: a nationwide linked cohort study.Respiratory research · 2026Article
- Article
- Expiratory Muscle Strength, Peak Oxygen Consumption and Hyperinflation Predicts Severe Exacerbation in Chronic Obstructive Pulmonary Disease Patients.Thoracic research and practice · 2026Article
- Determinants of poor chronic obstructive pulmonary disease control.The Libyan journal of medicine · 2025Article
- Article
- Non-pharmacologic Prevention of Acute Exacerbation Chronic Obstructive Pulmonary Disease.Tuberculosis and respiratory diseases · 2025Article
- Development and Validation of Machine Learning-Based Models for Prediction of Intensive Care Unit Admission and In-Hospital Mortality in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- From Atmosphere to Health Outcomes: Analyzing Predictors of Respiratory Disease Mortality in Turkiye.Public health challenges · 2024Article
- Time series analysis of the interaction between ambient temperature and air pollution on hospitalizations for AECOPD in Ganzhou, China.Scientific reports · 2024Article
- Deciphering the impact of microbial interactions on COPD exacerbation: An in-depth analysis of the lung microbiome.Heliyon · 2024Article
- Predicting Asthma Exacerbation Risk in the Adult South Korean Population Using Integrated Health Data and Machine Learning Models.Journal of asthma and allergy · 2024Article
- Modelling the longitudinal measurement of chronic obstructive pulmonary disease outpatient follow-up in the northwestern Ethiopia.Scientific reports · 2023Article
- Joint modeling of forced vital capacity measures with time to onset of polycythemia among chronic obstructive pulmonary outpatients follows-up: A case of University of Gondar Referral Hospital.Health science reports · 2023Article
- Intelligent Clinical Decision Support System for Managing COPD Patients.Journal of personalized medicine · 2023Article
- Extracellular vesicles and COPD: foe or friend?Journal of nanobiotechnology · 2023Review
- Association between the temperature difference and acute exacerbations of chronic obstructive pulmonary disease: A time-series analysis with 143,318 hospital admissions in Beijing, China.Frontiers in public health · 2023Article
- Observational
- Effect of high-level fine particulate matter and its interaction with meteorological factors on AECOPD in Shijiazhuang, China.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preventing exacerbation in chronic obstructive pulmonary disease (COPD) patients is crucial, but requires identification of the exacerbating factors. To date, no integrated analysis of patient-derived and external factors has been reported. To identify factors associated with COPD exacerbation, we collected data, including smoking status, lung function, and COPD assessment test scores, from 594 COPD patients in the Korean COPD subgroup study (KOCOSS), and merged these data with patients' Korean Health Insurance Review and Assessment Service data for 2007-2012. We also collected primary weather variables, including levels of particulate matter <10 microns in diameter, daily minimum ambient temperature, as well as respiratory virus activities, and the logs of web queries on COPD-related issues. We then assessed the associations between these patient-derived and external factors and COPD exacerbations. Univariate analysis showed that patient factors, air pollution, various types of viruses, temperature, and the number of COPD-related web queries were associated with COPD exacerbation. Multivariate analysis revealed that the number of exacerbations in the preceding year, female sex, COPD grade, and influenza virus detection rate, and lowest temperature showed significant association with exacerbation. Our findings may help COPD patients predict when exacerbations are likely, and provide intervention as early as possible.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.