Evidence map›Paper›PMID 31040179›Full record

ArticleThe Journal of biological chemistry2019

Mitochondria export iron-sulfur and sulfur intermediates to the cytoplasm for iron-sulfur cluster assembly and tRNA thiolation in yeast.

Ashutosh K Pandey, Jayashree Pain, Andrew Dancis, Debkumar Pain

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 77 citations in OpenAlex.

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  15. Mitochondria function in cytoplasmic FeS protein biogenesis.Biochimica et biophysica acta. Molecular cell research · 2024
    Review
  16. Requirements for the biogenesis of [2Fe-2S] proteins in the human and yeast cytosol.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Cytosolic iron-sulfur protein assembly system identifies clients by a C-terminal tripeptide.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Yeast Mitochondria Import Aqueous FeJournal of the American Chemical Society · 2023
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ashutosh K PandeyFrom the Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, Newark, New Jersey 07103 and.
Jayashree PainFrom the Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, Newark, New Jersey 07103 and.
Andrew Dancisthe Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Debkumar PainFrom the Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, Newark, New Jersey 07103 and painde@njms.rutgers.edu.
Rutgers, The State University of New Jersey · USUniversity of Pennsylvania · US

Funding

Mitochondria-cytoplasm interactions for cytosolic Fe-S cluster assemblyR01GM107542 · NIGMS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI DANCIS, ANDREW B., PAIN, DEBKUMAR · 2014 to 2023
$4.5M
NIGMS NIH HHS R01 GM107542
6 · The paper itself

Abstract

Iron-sulfur clusters are essential cofactors of proteins. In eukaryotes, iron-sulfur cluster biogenesis requires a mitochondrial iron-sulfur cluster machinery (ISC) and a cytoplasmic iron-sulfur protein assembly machinery (CIA). Here we used mitochondria and cytoplasm isolated from yeast cells, and [

Indexed as

Biological TransportCytoplasmIronIron-Sulfur ProteinsMitochondrial ProteinsRNA, FungalRNA, TransferSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSulfhydryl CompoundsSulfurIronIron-Sulfur ProteinsMitochondrial ProteinsRNA, FungalRNA, TransferSaccharomyces cerevisiae ProteinsSulfhydryl CompoundsSulfurABC transportercytoplasmexportironiron–sulfur proteinmetal cofactormitochondriasulfurtRNA thiolationyeast

Identifiers

PMID31040179
PMCPMC6579456
OpenAlexW2943312188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.