ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019
Inflammatory Potential of Diet, Inflammation-Related Lifestyle Factors, and Risk of Pancreatic Cancer: Results from the NIH-AARP Diet and Health Study.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Dietary inflammatory index and risk of major digestive tract cancers: a GRADE-assessed systematic review and dose-response meta-analysis.BMC cancer · 2026Pooled it
- Dietary Inflammatory Index in relation to Type 2 Diabetes: A Meta-Analysis.International journal of clinical practice · 2022Pooled it
- Dietary inflammatory index and pancreatic cancer risk: a systematic review and dose-response meta-analysis.Public health nutrition · 2021Pooled it
- Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies.Digestive diseases and sciences · 2021Pooled it
- Anti-inflammatory Diet Before Diagnosis and Survival After Urologic Cancer: Findings from Two Swedish Prospective Cohorts.European urology open science · 2026Article
- Meat Consumption in Relation to Colorectal Cancer Incidence in Anatomical Subsites in the National Institutes of Health-AARP Diet and Health Study.Current developments in nutrition · 2025Article
- Article
- Dietary Inflammatory Potential, Inflammation-Related Lifestyle Factors, and Incident Anxiety Disorders: A Prospective Cohort Study.Nutrients · 2023Article
- Diet Quality and Pancreatic Cancer Incidence in the Multiethnic Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Adherence to 5 Diet Quality Indices and Pancreatic Cancer Risk in a Large US Prospective Cohort.American journal of epidemiology · 2022Observational
- Association between novel dietary and lifestyle inflammation indices with risk of breast cancer (BrCa): a case-control study.Nutrition journal · 2022Article
- Are Prediagnostic Biomarkers of Inflammation and an Empirically Based Proinflammatory Dietary Pattern Associated With Poorer Pancreatic Cancer Survival?Journal of the National Cancer Institute · 2021Article
- Pancreatic Cancer Exposome Profile to Aid Early Detection and Inform Prevention Strategies.Journal of clinical medicine · 2021Review
- Dietary patterns and cancer risk.Nature reviews. Cancer · 2020Review
- Review
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundChronic inflammation is implicated in pancreatic cancer, and can be modulated by diet and other lifestyle factors. We examined the association between Dietary Inflammatory Index (DII) scores and pancreatic cancer risk in the NIH-AARP Diet and Health Study, and examined effect modification by inflammation-related lifestyle factors, including body mass index, cigarette smoking, diabetes, alcohol drinking, and use of non-steroidal anti-inflammatory drugs.
methodsEnergy-adjusted DII scores (E-DII) were computed on the basis of food frequency questionnaire responses for foods and dietary supplements. Cox proportional hazards models were fitted and effect modification was examined by adding a cross-product of each effect modifier with E-DII quintile in the multivariable-adjusted model.
resultsThere were 2,824 primary incident pancreatic cancers diagnosed during a median of 13.4 years follow-up, and there was no association between E-DII scores and pancreatic cancer risk among either men [HR
conclusionsResults from this large prospective study did not support an association between inflammatory potential of diet and pancreatic cancer, or effect modification by other inflammation-related lifestyle factors. IMPACT: Inflammatory potential of diet may not be related to pancreatic cancer risk. Future cohort studies with more frequent dietary measures could be useful in determining the appropriate timing of dietary intake in relation to pancreatic cancer etiology.
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