ArticleParasites & vectors2019
Molecular prevalence and subtyping of Cryptosporidium hominis among captive long-tailed macaques (Macaca fascicularis) and rhesus macaques (Macaca mulatta) from Hainan Island, southern China.
Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Gastrointestinal Parasites in Humans and Rhesus Macaques: A Cross-Sectional Study in Bhaktapur, Nepal.Health science reports · 2025Article
- A review of recentCurrent research in parasitology & vector-borne diseases · 2025Review
- Multicopy subtelomeric genes underlie animal infectivity of divergent Cryptosporidium hominis subtypes.Nature communications · 2024Article
- Molecular Screening and Characterization of Enteric Protozoan Parasites and Microsporidia in Wild Ducks from Portugal.Animals : an open access journal from MDPI · 2024Article
- Prevalence of gastrointestinal parasites in captive mammals at Khon Kaen Zoo, Thailand.Veterinary world · 2023Article
- Decline inFrontiers in cellular and infection microbiology · 2022Article
- Zoonotic parasites in farmed exotic animals in China: Implications to public health.International journal for parasitology. Parasites and wildlife · 2021Article
- Intestinal Protists in Captive Non-human Primates and Their Handlers in Six European Zoological Gardens. Molecular Evidence of Zoonotic Transmission.Frontiers in veterinary science · 2021Article
- Cryptosporidiosis among Hemodialysis Patients in Jordan: First Preliminary Screening Surveillance.Tropical medicine and infectious disease · 2019Article
- Cryptosporidium parvum and Cryptosporidium hominis subtypes in crab-eating macaques.Parasites & vectors · 2019Article
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9 authors.
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Abstract
backgroundCryptosporidium is an important zoonotic parasite that is commonly found in non-human primates (NHPs). Consequently, there is the potential for transmission of this pathogen from NHPs to humans. However, molecular characterization of the isolates of Cryptosporidium from NHPs remains relatively poor. The aim of the present work was to (i) determine the prevalence; and (ii) perform a genetic characterization of the Cryptosporidium isolated from captive Macaca fascicularis and M. mulatta on Hainan Island in southern China.
methodsA total of 223 fresh fecal samples were collected from captive M. fascicularis (n = 193) and M. mulatta (n = 30). The fecal specimens were examined for the presence of Cryptosporidium spp. by polymerase chain reaction (PCR) and sequencing of the partial small subunit (SSU) rRNA gene. The Cryptosporidium-positive specimens were subtyped by analyzing the 60-kDa glycoprotein (gp60) gene sequence.
resultsCryptosporidium spp. were detected in 5.7% (11/193) of M. fascicularis. All of the 11 Cryptosporidium isolates were identified as C. hominis. Subtyping of nine of these isolates identified four unique gp60 subtypes of C. hominis. These included IaA20R3a (n = 1), IoA17a (n = 1), IoA17b (n = 1), and IiA17 (n = 6). Notably, subtypes IaA20R3a, IoA17a, and IoA17b were novel subtypes which have not been reported previously.
conclusionsTo our knowledge, this is the first reported detection of Cryptosporidium in captive M. fascicularis from Hainan Island. The molecular characteristics and subtypes of the isolates here provide novel insights into the genotypic variation in C. hominis.
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