Evidence map›Paper›PMID 31039691›Full record

ArticleJournal of the Royal Society, Interface2019

Maternal and fetal cardiometabolic recovery following ultrasound-guided high-intensity focused ultrasound placental vascular occlusion.

Caroline J Shaw, Ian Rivens, John Civale, Kimberley J Botting, Beth J Allison, Kirsty L Brain, Y Niu, Gail Ter Haar, Dino A Giussani, Christoph C Lees

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Royal Society, Interface, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
    Guideline
  2. Twin Reversed Arterial Perfusion Sequence: Prenatal Diagnosis and Treatment.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2022
    Review
  3. Early-onset twin-twin transfusion syndrome: Case series and systematic review.Australasian journal of ultrasound in medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Caroline J Shaw1 Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3EG , UK.
Ian Rivens3 Joint Department of Physics, Institute of Cancer Research , Sutton SM2 5NG , UK.
John Civale3 Joint Department of Physics, Institute of Cancer Research , Sutton SM2 5NG , UK.
Kimberley J Botting1 Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3EG , UK.
Beth J Allison1 Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3EG , UK.
Kirsty L Brain1 Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3EG , UK.
Y Niu1 Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3EG , UK.
Gail Ter Haar3 Joint Department of Physics, Institute of Cancer Research , Sutton SM2 5NG , UK.
Dino A Giussani1 Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3EG , UK.
Christoph C Lees2 Institute of Reproductive and Developmental Biology, Imperial College London , London W12 0HS , UK.
University of Cambridge · GBInstitute of Cancer Research · GBImperial College London · GB

Funding

British Heart Foundation
6 · The paper itself

Abstract

High-intensity focused ultrasound (HIFU) is a non-invasive method of selective placental vascular occlusion, providing a potential therapy for conditions such as twin-twin transfusion syndrome. In order to translate this technique into human studies, evidence of prolonged fetal recovery and maintenance of a healthy fetal physiology following exposure to HIFU is essential. At 116 ± 2 days gestation, 12 pregnant ewes were assigned to control ( n = 6) or HIFU vascular occlusion ( n = 6) groups and anaesthetized. Placental blood vessels were identified using colour Doppler ultrasound; HIFU-mediated vascular occlusion was performed through intact maternal skin (1.66 MHz, 5 s duration, in situ I

Indexed as

Fetofetal TransfusionFetusHigh-Intensity Focused Ultrasound AblationPlacentaUltrasonography, DopplerVascular DiseasesAnimalsFemaleHumansPregnancySheephigh-intensity focused ultrasoundplacental vasculaturepregnancyselective vascular occlusion

Identifiers

PMID31039691
PMCPMC6544891
OpenAlexW2943815516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.