Evidence map›Paper›PMID 31039103›Full record

GuidelineThe Journal of urology2019

Diagnosis and Treatment of Overactive Bladder (Non-Neurogenic) in Adults: AUA/SUFU Guideline Amendment 2019.

Deborah J Lightner, Alexander Gomelsky, Lesley Souter, Sandip P Vasavada

15 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in The Journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 15 registered trials, which are not on this map. Cited by 248 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
248citing papers in PubMed, 17 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04120545 nacompletednot on this map

Effectiveness of Microcurrents Therapy in Overactive Bladder : Controlled and Randomized Triple Blind Clinical Trial

TypeinterventionalSponsorUniversity of Las Palmas de Gran CanariaRan2019 to 2021Enrolled56ConditionsOveractive Bladder, Urinary IncontinenceArmsMicrocurrents, Placebo Microcurrents
NCT04807920 phase4unknown statusnot on this mapstarted 2021, after this paper: background citation

Intravesical OnabotulinumtoxinA Injection at the Time of Prolapse Surgery for the Treatment of Overactive Bladder Syndrome: a Randomized Controlled Trial

TypeinterventionalSponsorWalter Reed National Military Medical CenterRan2021 to 2023Enrolled138ConditionsUrinary Bladder, Overactive, Pelvic Organ ProlapseArmsOnabotulinumtoxinA 100 UNT, Injectable saline
NCT05099419 early_phase1unknown statusnot on this mapstarted 2021, after this paper: background citation

Motor Cortical Neuromodulation With Repetitive Transcranial Magnetic Stimulation in Women With Overactive Bladder and Urgency Urinary Incontinence

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2022Enrolled10ConditionsOveractive Bladder, Urge IncontinenceArmsRepetitive Transcranial Magnetic Stimulation
NCT05309993 naterminatednot on this mapstarted 2022, after this paper: background citation

INvestigation of TENS Efficacy Versus Posterior Tibial Nerve Stimulation for Overactive Bladder

TypeinterventionalSponsorUniversity of New MexicoRan2022 to 2025Enrolled27ConditionsOveractive Bladder, Overactive Bladder Syndrome, Urinary Urge Incontinence, Urinary Bladder, OveractiveArmsPTNS, TENS
NCT05464589 nacompletednot on this mapstarted 2021, after this paper: background citation

Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults: A Randomized Control Trial

TypeinterventionalSponsorDow University of Health SciencesRan2021 to 2022Enrolled60ConditionsOveractive Bladder, Urge Incontinence, NocturiaArmsTranscutaneous tibial nerve stimulation along with pelvic floor muscle srengthening, Pelvic floor muscles strengthening
NCT05798403 narecruitingnot on this mapstarted 2023, after this paper: background citation

Electroacupuncture Versus Solifenacin Succinate for Female Overactive Bladder: A Multicenter, Randomized, Controlled, Noninferiority Trial

TypeinterventionalSponsorYin PingRan2023 to 2025Enrolled204ConditionsOveractive BladderArmselectroacupuncture, Solifenacin Succinate Tablets
NCT05968885 phase4recruitingnot on this mapstarted 2021, after this paper: background citation

Evaluation of the Efficacy and Urodynamic Outcomes Between Intradetrusor onabotulinumtoxinA Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity

TypeinterventionalSponsorMackay Memorial HospitalRan2021 to 2026Enrolled300ConditionsUrinary Bladder, Overactive, Urodynamics, Effect of DrugArmsIntradetrusor Botox® (onabotulinumtoxinA) injection, Combine Mirabegron and Solifenacin.
NCT06162065 phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Effectiveness of Oral Boldo in Improving Urinary Symptoms and Body Stability in Women Diagnosed With Overactive Bladder

TypeinterventionalSponsorUniversidad de ValparaisoRan2023 to 2024Enrolled10ConditionsUrinary Bladder, OveractiveArmsOxybutynin Pill, Boldo supplement
NCT06197295 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Solifenacin Combined With Mirabegron Versus Solifenacin With Vaginal Estrogen Cream for the Treatment of Detrusor Overactivity

TypeinterventionalSponsorMackay Memorial HospitalRan2022 to 2026Enrolled200ConditionsUrinary Bladder, Overactive, Effect of DrugArmsSolifenacin with vaginal estrogen cream, Combination pharmacotherapy
NCT06479720 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Solifenacin or Mirabegron With Local Estrogen Versus Combination Treatment With Mirabegron and Solifenacin for Refractory Overactive Bladder

TypeinterventionalSponsorMackay Memorial HospitalRan2022 to 2026Enrolled300ConditionsEffect of Drug, Urinary Bladder, OveractiveArmsCombined pharmacotherapy with Solifenacin and Mirabegron, Solifenacin with vaginal estrogen cream, Mirabegron with vaginal estrogen cream
NCT06797245 narecruitingnot on this mapstarted 2025, after this paper: background citation

The APPROVE Trial: A Randomized Controlled Trial Evaluating the Efficacy and Safety of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women

TypeinterventionalSponsorMedstar Health Research InstituteRan2025 to 2028Enrolled596ConditionsOveractive Bladder (OAB), Urinary Urgency, Urinary Urge Incontinence (UUI), NocturiaArmsRiSolve App, AUGS Patient Handouts
NCT07171424 nacompletednot on this mapstarted 2026, after this paper: background citation

Moving Beyond p-Values: Minimal Clinically Important Difference for Overactive Bladder Questionnaire - Version 8 and International Consultation on Incontinence Questionnaire - Short Form in Patients With Overactive Bladder Syndrome

TypeinterventionalSponsorArtvin Coruh UniversityRan2026 to 2026Enrolled104ConditionsOveractive Bladder SyndromeArmsBehavioral therapy and transcutaneous posterior tibial nerve stimulation
NCT07206446 nacompletednot on this mapstarted 2025, after this paper: background citation

A Prospective Evaluation of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women: The RiSolve Trial

TypeinterventionalSponsorUniversity of GalwayRan2025 to 2026Enrolled46ConditionsOveractive Bladder (OAB), Over Active BladderArmsRiSolve
NCT07377929 recruitingnot on this mapstarted 2026, after this paper: background citation

Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms

TypeobservationalSponsorBenaroya Research InstituteRan2026 to 2027Enrolled20ConditionsBenign Prostatic Hypertrophy (BPH), Lower Urinary Track SymptomsArmsSurvey using a questionnaire.
NCT07635212 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating the Efficacy of Probiotics as an Adjunct to Behavioral Therapy in Patients With Overactive Bladder (OAB) and Anxiety Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial

TypeinterventionalSponsorQilu Hospital of Shandong UniversityRan2026 to 2028Enrolled218ConditionsOveractive Bladder (OAB)ArmsMulti-strain Probiotic Compound, Placebo
3 · Its place in the literature

Who cites it

248 citing papers in PubMed, 17 syntheses or guidelines pooled it.

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  6. Bladder training for treating overactive bladder in adults.The Cochrane database of systematic reviews · 2023
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  8. Guideline
  9. Mirabegron and Anticholinergics in the Treatment of Overactive Bladder Syndrome: A Meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
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188 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Deborah J LightnerAmerican Urological Association Education and Research, Inc., Linthicum, Maryland.
Alexander GomelskyAmerican Urological Association Education and Research, Inc., Linthicum, Maryland.
Lesley SouterAmerican Urological Association Education and Research, Inc., Linthicum, Maryland.
Sandip P VasavadaAmerican Urological Association Education and Research, Inc., Linthicum, Maryland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this guideline is to provide a clinical framework for the diagnosis and treatment of non-neurogenic overactive bladder (OAB). MATERIALS &

methodsThe primary source of evidence for the original version of this guideline was the systematic review and data extraction conducted as part of the Agency for Healthcare Research and Quality (AHRQ) Evidence Report/Technology Assessment Number 187 titled Treatment of Overactive Bladder in Women (2009). That report was supplemented with additional searches capturing literature published through December 2011. Following initial publication, this guideline underwent amendment in 2014 and 2018. The current document reflects relevant literature published through October 2018.

resultsWhen sufficient evidence existed, the body of evidence for a particular treatment was assigned a strength rating of A (high), B (moderate), or C (low). Such statements are provided as Standards, Recommendations, or Options. In instances of insufficient evidence, additional guidance information is provided as Clinical Principles and Expert Opinions.

conclusionsThe evidence-based statements are provided for diagnosis and overall management of OAB, as well as for the various treatments. Diagnosis and treatment methodologies can be expected to change as the evidence base grows and as new treatment strategies become obtainable.

Indexed as

AdultAgedAged, 80 and overCritical PathwaysDiagnosis, DifferentialEvidence-Based MedicineFemaleHumansMiddle AgedOutcome Assessment, Health CareRandomized Controlled Trials as TopicSocieties, MedicalUnited StatesUrinary Bladder, OveractiveUrologyguidelinenocturiaoveractiveurinary bladderurinary incontinence

Identifiers

PMID31039103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 9 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.